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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL26
All Species:
27.27
Human Site:
T585
Identified Species:
60
UniProt:
Q53HC5
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53HC5
NP_060786.1
615
68139
T585
V
Q
V
Y
N
T
D
T
D
E
W
E
R
D
L
Chimpanzee
Pan troglodytes
XP_001135338
699
77366
T669
V
Q
V
Y
N
T
D
T
D
E
W
E
R
D
L
Rhesus Macaque
Macaca mulatta
XP_001114706
615
68091
T585
V
Q
V
Y
N
T
D
T
D
E
W
E
R
D
L
Dog
Lupus familis
XP_541933
587
65826
T557
V
Q
V
Y
N
T
E
T
D
E
W
E
R
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGY4
606
67013
T576
V
Q
V
Y
N
T
E
T
D
E
W
E
R
D
L
Rat
Rattus norvegicus
Q66HD2
613
69917
A570
V
Q
V
Y
D
R
E
A
N
R
W
S
R
G
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514871
587
65661
T557
V
Q
V
Y
N
T
E
T
D
E
W
E
R
D
L
Chicken
Gallus gallus
Q5ZLD3
629
70952
K587
V
Q
K
Y
D
P
E
K
D
E
W
H
K
V
F
Frog
Xenopus laevis
NP_001086711
635
71326
R593
V
Q
K
Y
D
P
E
R
D
E
W
H
K
V
F
Zebra Danio
Brachydanio rerio
Q5RGB8
605
68516
T575
V
Q
V
Y
N
T
E
T
D
E
W
E
R
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
Q584
V
Y
D
P
E
T
N
Q
W
R
L
C
G
C
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.9
99.8
92.6
N.A.
85.5
36
N.A.
84
40.2
39.8
75.9
N.A.
31.6
N.A.
N.A.
N.A.
Protein Similarity:
100
87.9
99.8
93.8
N.A.
91.5
53.9
N.A.
89.9
58.5
57.7
87.4
N.A.
50
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
40
N.A.
93.3
40
40
93.3
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
60
N.A.
100
60
60
100
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
0
0
10
0
28
0
28
0
82
0
0
0
0
64
0
% D
% Glu:
0
0
0
0
10
0
64
0
0
82
0
64
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
19
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
10
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
19
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
19
0
0
0
0
10
0
0
0
0
19
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
64
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
64
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
19
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
91
0
0
0
0
0
10
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
10
0
10
0
19
0
0
73
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
73
0
64
0
0
0
0
0
0
0
% T
% Val:
100
0
73
0
0
0
0
0
0
0
0
0
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
91
0
0
0
0
% W
% Tyr:
0
10
0
91
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _