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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TSSC1
All Species:
29.09
Human Site:
S218
Identified Species:
58.18
UniProt:
Q53HC9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53HC9
NP_003301.1
387
43603
S218
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Chimpanzee
Pan troglodytes
XP_001151736
389
43783
S220
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Rhesus Macaque
Macaca mulatta
XP_001098087
243
27545
N81
S
Q
I
Y
C
I
E
N
A
H
G
Q
L
V
R
Dog
Lupus familis
XP_532856
435
49128
S266
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0G5
386
43152
S218
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Rat
Rattus norvegicus
Q5PPK9
386
43138
S218
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509323
547
60507
S378
G
W
D
T
R
S
M
S
Q
I
Y
C
I
E
N
Chicken
Gallus gallus
Frog
Xenopus laevis
Q3KPT3
387
43631
R218
G
W
D
I
R
S
M
R
Q
I
Y
C
I
E
N
Zebra Danio
Brachydanio rerio
Q5XJP1
387
43570
S218
G
W
D
L
R
S
M
S
Q
I
Y
C
I
E
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395260
375
42547
S208
G
W
D
F
R
N
P
S
E
A
S
W
T
I
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780046
219
25255
Q57
M
I
E
N
A
H
G
Q
L
V
R
D
L
D
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22607
507
55741
F224
G
H
Q
D
N
A
E
F
A
L
A
M
C
P
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.8
62.5
82.7
N.A.
93
93.2
N.A.
61.4
N.A.
86.8
85
N.A.
N.A.
51.6
N.A.
41.6
Protein Similarity:
100
96.6
62.5
85.7
N.A.
97.6
97.4
N.A.
66.5
N.A.
95.6
95.3
N.A.
N.A.
69.2
N.A.
47
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
33.3
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
100
100
N.A.
100
N.A.
86.6
93.3
N.A.
N.A.
46.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
37
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
9
0
0
17
9
9
0
0
0
0
% A
% Cys:
0
0
0
0
9
0
0
0
0
0
0
67
9
0
0
% C
% Asp:
0
0
75
9
0
0
0
0
0
0
0
9
0
9
0
% D
% Glu:
0
0
9
0
0
0
17
0
9
0
0
0
0
67
0
% E
% Phe:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
9
% F
% Gly:
84
0
0
0
0
0
9
0
0
0
9
0
0
0
0
% G
% His:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
9
9
9
0
9
0
0
0
67
0
0
67
9
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
9
0
0
0
0
9
9
0
0
17
0
9
% L
% Met:
9
0
0
0
0
0
67
0
0
0
0
9
0
0
0
% M
% Asn:
0
0
0
9
9
9
0
9
0
0
0
0
0
0
67
% N
% Pro:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% P
% Gln:
0
9
9
0
0
0
0
9
67
0
0
9
0
0
0
% Q
% Arg:
0
0
0
0
75
0
0
9
0
0
9
0
0
0
9
% R
% Ser:
9
0
0
0
0
67
0
67
0
0
9
0
0
0
0
% S
% Thr:
0
0
0
50
0
0
0
0
0
0
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
0
9
0
% V
% Trp:
0
75
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _