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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC50 All Species: 28.48
Human Site: Y149 Identified Species: 56.97
UniProt: Q53HI1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53HI1 NP_054763.2 259 30373 Y149 V K R Q S R D Y D V E W G Y A
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103333 259 30362 Y149 V K R Q S R D Y D V E W G Y A
Dog Lupus familis XP_854439 263 30965 Y149 V K R Q S R D Y D V E W G Y A
Cat Felis silvestris
Mouse Mus musculus Q9CQ61 259 30410 Y149 V K R Q S R D Y D V E W G Y A
Rat Rattus norvegicus O55227 259 30417 Y149 V K R Q S R D Y D V E W G Y A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKM1 259 30584 Y149 V K R Q G K D Y D V E W G Y T
Zebra Danio Brachydanio rerio Q7ZUU1 259 30535 Y147 M K H P N R D Y D V E W G Y A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHN5 275 32454 P165 L R T N S L E P D I E W G Y A
Honey Bee Apis mellifera XP_623081 267 31242 Q157 Y L R I D K T Q D V E W G Y A
Nematode Worm Caenorhab. elegans Q10045 301 34720 V182 R K V R D Q D V E W G Y C F D
Sea Urchin Strong. purpuratus XP_785090 267 30975 Q156 L L I S H R G Q D V E W G Y A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36125 273 31975 S169 K F K S S Q N S V V E W A Y C
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.3 N.A. 95.7 96.1 N.A. N.A. N.A. 84.9 79.5 N.A. 51.6 49.8 41.2 58.8
Protein Similarity: 100 N.A. 99.2 97.7 N.A. 98.8 98.4 N.A. N.A. N.A. 91.5 89.9 N.A. 69.4 65.9 56.8 71.9
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 80 73.3 N.A. 46.6 53.3 13.3 53.3
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 86.6 86.6 N.A. 73.3 60 46.6 60
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 57.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 33.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 75 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % C
% Asp: 0 0 0 0 17 0 67 0 84 0 0 0 0 0 9 % D
% Glu: 0 0 0 0 0 0 9 0 9 0 92 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 0 9 0 9 0 0 0 9 0 84 0 0 % G
% His: 0 0 9 0 9 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 9 9 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 9 67 9 0 0 17 0 0 0 0 0 0 0 0 0 % K
% Leu: 17 17 0 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 9 0 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 0 9 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 50 0 17 0 17 0 0 0 0 0 0 0 % Q
% Arg: 9 9 59 9 0 59 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 17 59 0 0 9 0 0 0 0 0 0 0 % S
% Thr: 0 0 9 0 0 0 9 0 0 0 0 0 0 0 9 % T
% Val: 50 0 9 0 0 0 0 9 9 84 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 92 0 0 0 % W
% Tyr: 9 0 0 0 0 0 0 59 0 0 0 9 0 92 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _