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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UNC50 All Species: 44.85
Human Site: Y64 Identified Species: 89.7
UniProt: Q53HI1 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53HI1 NP_054763.2 259 30373 Y64 F T S P Q R V Y R N F H Y R K
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103333 259 30362 Y64 F T S P Q R V Y R N F H Y R K
Dog Lupus familis XP_854439 263 30965 Y64 F T S P Q R V Y R N F H Y R K
Cat Felis silvestris
Mouse Mus musculus Q9CQ61 259 30410 Y64 F T S P Q R V Y R N F H Y R K
Rat Rattus norvegicus O55227 259 30417 Y64 F T S P Q R V Y R N F H Y R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6DKM1 259 30584 Y64 F T S P Q K V Y R N F H Y R K
Zebra Danio Brachydanio rerio Q7ZUU1 259 30535 Y62 F T S P Q K V Y R N F H Y R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VHN5 275 32454 Y81 F V A P Q K V Y R N F N Y R K
Honey Bee Apis mellifera XP_623081 267 31242 Y74 F I S P Q K V Y R N F Q N R K
Nematode Worm Caenorhab. elegans Q10045 301 34720 Y97 L I Q P S K V Y K N F I Y R K
Sea Urchin Strong. purpuratus XP_785090 267 30975 Y72 L V A P Q K V Y R N F Q Y R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36125 273 31975 Y72 I F H P R K A Y R S I Y Y Q R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 99.2 97.3 N.A. 95.7 96.1 N.A. N.A. N.A. 84.9 79.5 N.A. 51.6 49.8 41.2 58.8
Protein Similarity: 100 N.A. 99.2 97.7 N.A. 98.8 98.4 N.A. N.A. N.A. 91.5 89.9 N.A. 69.4 65.9 56.8 71.9
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 93.3 93.3 N.A. 73.3 73.3 53.3 66.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. N.A. N.A. 100 100 N.A. 93.3 80 66.6 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. 35.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 57.8 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 17 0 0 0 9 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 75 9 0 0 0 0 0 0 0 0 92 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 59 0 0 0 % H
% Ile: 9 17 0 0 0 0 0 0 0 0 9 9 0 0 0 % I
% Lys: 0 0 0 0 0 59 0 0 9 0 0 0 0 0 92 % K
% Leu: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 92 0 9 9 0 0 % N
% Pro: 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 9 0 84 0 0 0 0 0 0 17 0 9 0 % Q
% Arg: 0 0 0 0 9 42 0 0 92 0 0 0 0 92 9 % R
% Ser: 0 0 67 0 9 0 0 0 0 9 0 0 0 0 0 % S
% Thr: 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 17 0 0 0 0 92 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 100 0 0 0 9 92 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _