KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM177
All Species:
20.91
Human Site:
Y250
Identified Species:
51.11
UniProt:
Q53S58
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53S58
NP_001098668.1
311
33760
Y250
A
C
G
G
V
E
F
Y
E
K
L
L
S
G
N
Chimpanzee
Pan troglodytes
XP_001157041
311
33789
Y250
A
C
G
G
V
E
F
Y
E
K
L
L
S
G
N
Rhesus Macaque
Macaca mulatta
XP_001084260
311
34178
Y250
V
C
G
G
V
E
F
Y
E
K
L
L
S
G
N
Dog
Lupus familis
XP_533321
875
98723
Y814
A
Q
G
G
V
E
F
Y
E
K
I
L
S
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q8BPE4
311
34049
Y250
V
Q
G
G
V
E
F
Y
E
K
I
L
S
G
N
Rat
Rattus norvegicus
Q4KM93
311
33983
Y250
V
R
G
G
V
E
F
Y
E
K
I
L
S
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_422081
304
32946
E245
D
Y
A
K
G
G
V
E
F
Y
D
K
I
L
S
Frog
Xenopus laevis
Q66IS8
310
34180
G250
S
K
S
Y
A
T
G
G
I
E
F
Y
E
K
I
Zebra Danio
Brachydanio rerio
Q6PBI8
310
34011
L250
R
D
Y
A
K
G
G
L
E
F
Y
E
K
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798641
308
34306
G249
K
L
L
Q
K
N
R
G
L
R
S
L
L
G
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
91.3
29.4
N.A.
78.4
78.7
N.A.
N.A.
43.7
42.4
42.1
N.A.
N.A.
N.A.
N.A.
27.3
Protein Similarity:
100
99.3
94.8
32.9
N.A.
85.8
86.8
N.A.
N.A.
57.8
62.3
60.4
N.A.
N.A.
N.A.
N.A.
47.9
P-Site Identity:
100
100
93.3
86.6
N.A.
80
80
N.A.
N.A.
0
0
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
86.6
86.6
N.A.
N.A.
6.6
13.3
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
10
10
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
0
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
60
0
10
70
10
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
60
0
10
10
10
0
0
0
0
% F
% Gly:
0
0
60
60
10
20
20
20
0
0
0
0
0
70
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
30
0
10
10
10
% I
% Lys:
10
10
0
10
20
0
0
0
0
60
0
10
10
10
10
% K
% Leu:
0
10
10
0
0
0
0
10
10
0
30
70
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
60
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
20
0
10
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
10
0
0
0
0
10
0
0
10
0
0
0
0
0
% R
% Ser:
10
0
10
0
0
0
0
0
0
0
10
0
60
0
10
% S
% Thr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
30
0
0
0
60
0
10
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
10
10
0
0
0
60
0
10
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _