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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
INO80D
All Species:
19.7
Human Site:
S218
Identified Species:
39.39
UniProt:
Q53TQ3
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q53TQ3
NP_060229.3
878
98174
S218
H
L
S
P
L
S
T
S
L
K
P
P
A
P
P
Chimpanzee
Pan troglodytes
XP_001136877
878
98146
S218
H
L
S
P
L
S
T
S
L
K
P
P
A
P
P
Rhesus Macaque
Macaca mulatta
XP_001105620
878
98016
S218
H
L
S
P
L
S
T
S
L
K
P
P
A
P
P
Dog
Lupus familis
XP_545610
1029
113446
K220
S
P
L
S
T
S
L
K
P
P
A
P
P
P
P
Cat
Felis silvestris
Mouse
Mus musculus
Q66JY2
873
97450
S214
H
L
S
P
L
S
T
S
L
K
P
P
A
P
P
Rat
Rattus norvegicus
XP_001070910
1021
112403
S213
H
L
S
P
L
P
T
S
L
K
P
P
A
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507557
887
99047
S231
L
P
P
L
S
T
S
S
K
P
P
G
P
P
P
Chicken
Gallus gallus
XP_421957
902
100650
L220
H
L
P
P
S
S
A
L
L
K
P
T
G
L
P
Frog
Xenopus laevis
Q566I1
812
91300
E185
W
Q
R
L
R
E
T
E
I
V
N
V
H
Q
E
Zebra Danio
Brachydanio rerio
A1L1F6
843
93561
P205
A
T
Q
T
P
I
N
P
S
S
P
R
A
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121602
487
54565
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001193176
1005
112051
R223
R
L
Q
E
K
L
E
R
N
K
Q
R
L
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.3
81.9
N.A.
93.2
80.3
N.A.
91
88.8
69.8
45
N.A.
N.A.
22.3
N.A.
24.8
Protein Similarity:
100
99.8
99.3
83.3
N.A.
95.6
82.8
N.A.
93.1
91.8
78
57.9
N.A.
N.A.
34.7
N.A.
40.5
P-Site Identity:
100
100
100
26.6
N.A.
100
93.3
N.A.
26.6
53.3
6.6
13.3
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
93.3
N.A.
40
53.3
13.3
13.3
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
9
0
0
0
9
0
50
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
9
0
9
9
9
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% G
% His:
50
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
9
59
0
0
0
0
0
% K
% Leu:
9
59
9
17
42
9
9
9
50
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
0
9
0
9
0
0
0
0
% N
% Pro:
0
17
17
50
9
9
0
9
9
17
67
50
17
59
67
% P
% Gln:
0
9
17
0
0
0
0
0
0
0
9
0
0
9
9
% Q
% Arg:
9
0
9
0
9
0
0
9
0
0
0
17
0
9
0
% R
% Ser:
9
0
42
9
17
50
9
50
9
9
0
0
0
0
0
% S
% Thr:
0
9
0
9
9
9
50
0
0
0
0
9
0
0
9
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _