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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80D All Species: 9.39
Human Site: T165 Identified Species: 18.79
UniProt: Q53TQ3 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53TQ3 NP_060229.3 878 98174 T165 D D L K K G A T V R K K L Q S
Chimpanzee Pan troglodytes XP_001136877 878 98146 T165 D D L K K G A T V R K K L Q S
Rhesus Macaque Macaca mulatta XP_001105620 878 98016 T165 D D L K K G A T V R K K L Q S
Dog Lupus familis XP_545610 1029 113446 R167 L K K G A T V R K K L Q S K L
Cat Felis silvestris
Mouse Mus musculus Q66JY2 873 97450 L161 F N E E D D D L K K G V T V R
Rat Rattus norvegicus XP_001070910 1021 112403 L160 F N E E D D D L K K G V T V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507557 887 99047 R178 Q S K L A Q N R Q R Q R E T E
Chicken Gallus gallus XP_421957 902 100650 R167 L K K G A T V R K K L Q S K L
Frog Xenopus laevis Q566I1 812 91300 S132 G H D G L N L S P P G A R L P
Zebra Danio Brachydanio rerio A1L1F6 843 93561 F152 M L K S S G A F L K K P Q E T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121602 487 54565
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193176 1005 112051 L170 F E L N D L S L M C R S R P P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.3 81.9 N.A. 93.2 80.3 N.A. 91 88.8 69.8 45 N.A. N.A. 22.3 N.A. 24.8
Protein Similarity: 100 99.8 99.3 83.3 N.A. 95.6 82.8 N.A. 93.1 91.8 78 57.9 N.A. N.A. 34.7 N.A. 40.5
P-Site Identity: 100 100 100 0 N.A. 0 0 N.A. 6.6 0 0 20 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 20 N.A. 20 20 N.A. 20 20 6.6 46.6 N.A. N.A. 0 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 25 0 34 0 0 0 0 9 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % C
% Asp: 25 25 9 0 25 17 17 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 17 17 0 0 0 0 0 0 0 0 9 9 9 % E
% Phe: 25 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 25 0 34 0 0 0 0 25 0 0 0 0 % G
% His: 0 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 17 34 25 25 0 0 0 34 42 34 25 0 17 0 % K
% Leu: 17 9 34 9 9 9 9 25 9 0 17 0 25 9 17 % L
% Met: 9 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % M
% Asn: 0 17 0 9 0 9 9 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 9 0 9 0 9 17 % P
% Gln: 9 0 0 0 0 9 0 0 9 0 9 17 9 25 0 % Q
% Arg: 0 0 0 0 0 0 0 25 0 34 9 9 17 0 17 % R
% Ser: 0 9 0 9 9 0 9 9 0 0 0 9 17 0 25 % S
% Thr: 0 0 0 0 0 17 0 25 0 0 0 0 17 9 9 % T
% Val: 0 0 0 0 0 0 17 0 25 0 0 17 0 17 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _