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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: INO80D All Species: 33.33
Human Site: T238 Identified Species: 66.67
UniProt: Q53TQ3 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q53TQ3 NP_060229.3 878 98174 T238 K S P Q P Q N T S L P M Q G V
Chimpanzee Pan troglodytes XP_001136877 878 98146 T238 K S P Q P Q N T S L P M Q G V
Rhesus Macaque Macaca mulatta XP_001105620 878 98016 T238 K S P Q P Q N T S L P M Q G V
Dog Lupus familis XP_545610 1029 113446 T240 K S P P P P N T S L P M Q G V
Cat Felis silvestris
Mouse Mus musculus Q66JY2 873 97450 T234 K S P Q P Q N T S L P M Q G V
Rat Rattus norvegicus XP_001070910 1021 112403 T233 K S P Q P Q S T S L P M Q G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507557 887 99047 T251 K S P Q P P N T S L P M Q G V
Chicken Gallus gallus XP_421957 902 100650 T240 K S P Q P P N T S L P M Q G V
Frog Xenopus laevis Q566I1 812 91300 S205 P A H S P L Q S P S L Q E Q H
Zebra Danio Brachydanio rerio A1L1F6 843 93561 S225 G S L F K T S S S L Q D T H Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121602 487 54565
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001193176 1005 112051 H243 I L A K S M Q H T Q F T N A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 99.3 81.9 N.A. 93.2 80.3 N.A. 91 88.8 69.8 45 N.A. N.A. 22.3 N.A. 24.8
Protein Similarity: 100 99.8 99.3 83.3 N.A. 95.6 82.8 N.A. 93.1 91.8 78 57.9 N.A. N.A. 34.7 N.A. 40.5
P-Site Identity: 100 100 100 86.6 N.A. 100 93.3 N.A. 93.3 93.3 6.6 20 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 100 86.6 N.A. 100 100 N.A. 93.3 93.3 26.6 33.3 N.A. N.A. 0 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 0 0 0 0 0 0 0 0 0 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % E
% Phe: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 0 0 0 0 0 67 0 % G
% His: 0 0 9 0 0 0 0 9 0 0 0 0 0 9 9 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 67 0 0 9 9 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 9 9 0 0 9 0 0 0 75 9 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 0 0 67 0 0 0 % M
% Asn: 0 0 0 0 0 0 59 0 0 0 0 0 9 0 0 % N
% Pro: 9 0 67 9 75 25 0 0 9 0 67 0 0 0 0 % P
% Gln: 0 0 0 59 0 42 17 0 0 9 9 9 67 9 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 75 0 9 9 0 17 17 75 9 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 9 0 67 9 0 0 9 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 67 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _