KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTBL2
All Species:
52.12
Human Site:
T279
Identified Species:
95.56
UniProt:
Q562R1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q562R1
NP_001017992.1
376
42003
T279
S
S
G
I
H
E
T
T
F
N
S
I
M
K
C
Chimpanzee
Pan troglodytes
XP_001140995
376
42001
T279
S
S
G
I
H
E
T
T
F
N
S
I
M
K
C
Rhesus Macaque
Macaca mulatta
XP_001101792
376
41948
T279
S
S
G
I
H
E
T
T
F
N
S
I
M
K
C
Dog
Lupus familis
XP_544346
376
41898
T279
S
S
G
I
H
E
T
T
F
N
S
I
M
K
C
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFZ3
376
41986
T279
S
R
G
I
H
E
T
T
F
N
S
I
M
K
C
Rat
Rattus norvegicus
P60711
375
41718
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53478
376
41817
T279
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Frog
Xenopus laevis
P53505
376
41831
T279
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
T278
S
C
G
I
H
E
T
T
F
N
S
I
M
K
C
Fruit Fly
Dros. melanogaster
P10987
376
41803
T279
A
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Honey Bee
Apis mellifera
XP_393368
376
41787
T279
A
C
G
I
H
E
T
T
Y
N
S
I
M
K
C
Nematode Worm
Caenorhab. elegans
P10984
376
41759
S279
S
A
G
I
H
E
T
S
Y
N
S
I
M
K
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
96.8
N.A.
97
91.4
N.A.
N.A.
92
91.4
91.7
91.4
90.6
90.6
90.1
N.A.
Protein Similarity:
100
99.7
98.9
98.6
N.A.
98.6
96.5
N.A.
N.A.
96.2
96.2
96.5
96.8
96.2
96.5
96.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
93.3
80
80
80
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
N.A.
93.3
93.3
93.3
93.3
93.3
93.3
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
54
0
0
0
0
0
0
0
0
0
0
0
0
100
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
77
0
0
0
0
0
0
% F
% Gly:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
100
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
85
31
0
0
0
0
0
8
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
100
93
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
24
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _