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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTBL2
All Species:
54.55
Human Site:
Y189
Identified Species:
100
UniProt:
Q562R1
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q562R1
NP_001017992.1
376
42003
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Chimpanzee
Pan troglodytes
XP_001140995
376
42001
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Rhesus Macaque
Macaca mulatta
XP_001101792
376
41948
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Dog
Lupus familis
XP_544346
376
41898
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BFZ3
376
41986
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Rat
Rattus norvegicus
P60711
375
41718
Y188
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53478
376
41817
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Frog
Xenopus laevis
P53505
376
41831
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
Y188
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
Y188
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Fruit Fly
Dros. melanogaster
P10987
376
41803
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Honey Bee
Apis mellifera
XP_393368
376
41787
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Nematode Worm
Caenorhab. elegans
P10984
376
41759
Y189
A
G
R
D
L
T
D
Y
L
M
K
I
L
T
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
96.8
N.A.
97
91.4
N.A.
N.A.
92
91.4
91.7
91.4
90.6
90.6
90.1
N.A.
Protein Similarity:
100
99.7
98.9
98.6
N.A.
98.6
96.5
N.A.
N.A.
96.2
96.2
96.5
96.8
96.2
96.5
96.8
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
100
100
100
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
100
100
100
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
100
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% K
% Leu:
0
0
0
0
100
0
0
0
100
0
0
0
100
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
100
0
0
0
0
0
0
0
100
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _