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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO2
All Species:
8.18
Human Site:
S58
Identified Species:
22.5
UniProt:
Q56NI9
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56NI9
NP_001017420.1
601
68307
S58
Q
Q
E
H
F
V
L
S
A
L
K
T
T
E
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_543224
598
67974
S61
S
Q
Q
S
H
F
L
S
N
P
S
E
T
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8CIB9
592
67255
S68
H
Q
L
H
F
P
S
S
P
L
K
T
T
E
N
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508920
682
76075
I107
L
V
K
E
S
R
S
I
C
H
K
N
N
S
G
Chicken
Gallus gallus
XP_420012
679
73766
P115
P
L
Q
A
A
S
I
P
S
A
A
R
R
E
L
Frog
Xenopus laevis
NP_001089603
640
69941
T71
K
R
D
K
F
Y
V
T
P
L
D
R
K
L
I
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
S64
Q
R
A
F
L
L
E
S
P
P
K
R
V
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
K125
V
D
P
A
F
L
N
K
S
F
E
E
L
Q
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001146746
323
35496
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
74.2
N.A.
69
N.A.
N.A.
45.8
37.4
36.7
37.4
N.A.
N.A.
N.A.
N.A.
27.9
Protein Similarity:
100
N.A.
N.A.
84.1
N.A.
80
N.A.
N.A.
60.4
53.4
51.5
53.5
N.A.
N.A.
N.A.
N.A.
43
P-Site Identity:
100
N.A.
N.A.
26.6
N.A.
60
N.A.
N.A.
6.6
6.6
20
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
33.3
N.A.
60
N.A.
N.A.
13.3
33.3
53.3
33.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
21.6
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
31.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
0
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
23
12
0
0
0
12
12
12
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
0
12
12
0
0
0
0
0
0
0
12
0
0
0
0
% D
% Glu:
0
0
12
12
0
0
12
0
0
0
12
23
0
34
0
% E
% Phe:
0
0
0
12
45
12
0
0
0
12
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% G
% His:
12
0
0
23
12
0
0
0
0
12
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
12
12
0
0
0
0
0
0
23
% I
% Lys:
12
0
12
12
0
0
0
12
0
0
45
0
12
0
12
% K
% Leu:
12
12
12
0
12
23
23
0
0
34
0
0
12
12
12
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
12
0
0
12
12
0
12
% N
% Pro:
12
0
12
0
0
12
0
12
34
23
0
0
0
0
12
% P
% Gln:
23
34
23
0
0
0
0
0
0
0
0
0
0
12
0
% Q
% Arg:
0
23
0
0
0
12
0
0
0
0
0
34
12
0
12
% R
% Ser:
12
0
0
12
12
12
23
45
23
0
12
0
0
23
0
% S
% Thr:
0
0
0
0
0
0
0
12
0
0
0
23
34
12
0
% T
% Val:
12
12
0
0
0
12
12
0
0
0
0
0
12
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _