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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EAPP All Species: 23.94
Human Site: S81 Identified Species: 40.51
UniProt: Q56P03 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q56P03 NP_060923.2 285 32734 S81 K T M E D K L S S L G T G S S
Chimpanzee Pan troglodytes XP_509897 285 32735 S81 K T M E D K L S S L G T G S S
Rhesus Macaque Macaca mulatta XP_001104634 296 33316 S92 K T M E D K L S S L G T G S S
Dog Lupus familis XP_850430 286 32978 S81 K T M E D K L S S L E T G S S
Cat Felis silvestris
Mouse Mus musculus Q5BU09 281 32475 S81 K T M E D Q L S S L G T G S S
Rat Rattus norvegicus NP_001128459 280 32140 S81 T V E D K L S S L G T G S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512221 286 33024 Y81 R A M D D K L Y S P E R V S S
Chicken Gallus gallus XP_421235 287 33535 K81 R N I E G K W K S P E M G T S
Frog Xenopus laevis NP_001085682 293 33892 Q82 K T M E G S W Q S I V P V A S
Zebra Danio Brachydanio rerio NP_956078 307 34683 T84 G S W T A S T T Q G Q A T G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498165 467 53727 Y168 A A L E L L P Y D V D L T D S
Sea Urchin Strong. purpuratus XP_001197735 355 39844 F88 M I L H E K Q F R T D V E K K
Poplar Tree Populus trichocarpa XP_002307158 149 16865
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196449 150 17037
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 88.1 89.5 N.A. 87.3 87.7 N.A. 74.4 68.9 63.4 61.5 N.A. N.A. N.A. 23.9 41.6
Protein Similarity: 100 99.6 89.8 93.3 N.A. 91.2 91.9 N.A. 82.1 82.2 77.4 73.9 N.A. N.A. N.A. 37.2 59.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 20 N.A. 46.6 33.3 40 0 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 100 26.6 N.A. 60 53.3 53.3 20 N.A. N.A. N.A. 26.6 20
Percent
Protein Identity: 28.4 N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: 40 N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 15 0 0 8 0 0 0 0 0 0 8 0 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 43 0 0 0 8 0 15 0 0 8 0 % D
% Glu: 0 0 8 58 8 0 0 0 0 0 22 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 15 0 0 0 0 15 29 8 43 8 0 % G
% His: 0 0 0 8 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 8 0 0 0 0 0 0 8 0 0 0 0 0 % I
% Lys: 43 0 0 0 8 50 0 8 0 0 0 0 0 8 8 % K
% Leu: 0 0 15 0 8 15 43 0 8 36 0 8 0 0 0 % L
% Met: 8 0 50 0 0 0 0 0 0 0 0 8 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 8 0 0 15 0 8 0 0 0 % P
% Gln: 0 0 0 0 0 8 8 8 8 0 8 0 0 0 0 % Q
% Arg: 15 0 0 0 0 0 0 0 8 0 0 8 0 0 0 % R
% Ser: 0 8 0 0 0 15 8 43 58 0 0 0 8 50 72 % S
% Thr: 8 43 0 8 0 0 8 8 0 8 8 36 15 8 8 % T
% Val: 0 8 0 0 0 0 0 0 0 8 8 8 15 0 0 % V
% Trp: 0 0 8 0 0 0 15 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 15 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _