Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EAPP All Species: 26.06
Human Site: S88 Identified Species: 44.1
UniProt: Q56P03 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q56P03 NP_060923.2 285 32734 S88 S S L G T G S S S G N G K V A
Chimpanzee Pan troglodytes XP_509897 285 32735 S88 S S L G T G S S S G N G K V A
Rhesus Macaque Macaca mulatta XP_001104634 296 33316 S99 S S L G T G S S S G N G K V A
Dog Lupus familis XP_850430 286 32978 S88 S S L E T G S S S G T G K V G
Cat Felis silvestris
Mouse Mus musculus Q5BU09 281 32475 S88 S S L G T G S S S G V A K V G
Rat Rattus norvegicus NP_001128459 280 32140 S88 S L G T G S S S G V A K V G G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512221 286 33024 S88 Y S P E R V S S S G T E I T D
Chicken Gallus gallus XP_421235 287 33535 S88 K S P E M G T S S S T G E A G
Frog Xenopus laevis NP_001085682 293 33892 S89 Q S I V P V A S T S N G A T T
Zebra Danio Brachydanio rerio NP_956078 307 34683 T91 T Q G Q A T G T N D S T S A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_498165 467 53727 S175 Y D V D L T D S E V D P E M P
Sea Urchin Strong. purpuratus XP_001197735 355 39844 K95 F R T D V E K K L T A A T R A
Poplar Tree Populus trichocarpa XP_002307158 149 16865
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196449 150 17037
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 88.1 89.5 N.A. 87.3 87.7 N.A. 74.4 68.9 63.4 61.5 N.A. N.A. N.A. 23.9 41.6
Protein Similarity: 100 99.6 89.8 93.3 N.A. 91.2 91.9 N.A. 82.1 82.2 77.4 73.9 N.A. N.A. N.A. 37.2 59.1
P-Site Identity: 100 100 100 80 N.A. 80 20 N.A. 33.3 33.3 26.6 6.6 N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: 100 100 100 80 N.A. 80 20 N.A. 33.3 46.6 46.6 33.3 N.A. N.A. N.A. 33.3 6.6
Percent
Protein Identity: 28.4 N.A. N.A. 27.7 N.A. N.A.
Protein Similarity: 40 N.A. N.A. 40.3 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 0 N.A. N.A. 0 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 8 0 8 0 0 0 15 15 8 15 36 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 15 0 0 8 0 0 8 8 0 0 0 8 % D
% Glu: 0 0 0 22 0 8 0 0 8 0 0 8 15 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 15 29 8 43 8 0 8 43 0 43 0 8 29 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 8 0 0 0 0 0 8 8 0 0 0 8 36 0 0 % K
% Leu: 0 8 36 0 8 0 0 0 8 0 0 0 0 0 0 % L
% Met: 0 0 0 0 8 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 0 0 0 0 0 0 8 0 29 0 0 0 0 % N
% Pro: 0 0 15 0 8 0 0 0 0 0 0 8 0 0 8 % P
% Gln: 8 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 0 0 0 0 0 8 0 % R
% Ser: 43 58 0 0 0 8 50 72 50 15 8 0 8 0 0 % S
% Thr: 8 0 8 8 36 15 8 8 8 8 22 8 8 15 8 % T
% Val: 0 0 8 8 8 15 0 0 0 15 8 0 8 36 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _