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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAPP
All Species:
10.91
Human Site:
T248
Identified Species:
18.46
UniProt:
Q56P03
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56P03
NP_060923.2
285
32734
T248
D
A
A
E
K
A
E
T
D
V
E
E
I
Y
H
Chimpanzee
Pan troglodytes
XP_509897
285
32735
T248
D
A
A
E
K
A
E
T
D
V
E
E
I
Y
H
Rhesus Macaque
Macaca mulatta
XP_001104634
296
33316
T259
D
A
A
E
K
A
E
T
D
V
E
E
I
Y
H
Dog
Lupus familis
XP_850430
286
32978
A249
D
A
A
E
Q
T
E
A
Q
A
E
E
I
Y
H
Cat
Felis silvestris
Mouse
Mus musculus
Q5BU09
281
32475
R244
N
P
E
D
P
A
E
R
E
A
E
E
I
Y
H
Rat
Rattus norvegicus
NP_001128459
280
32140
E244
P
E
D
L
A
E
R
E
V
E
E
I
Y
H
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512221
286
33024
G249
T
A
T
E
E
Q
E
G
M
E
E
E
I
Y
H
Chicken
Gallus gallus
XP_421235
287
33535
Q250
T
T
P
A
Q
S
N
Q
E
E
E
E
V
Y
H
Frog
Xenopus laevis
NP_001085682
293
33892
E257
T
E
T
G
T
E
T
E
E
T
E
M
Y
H
P
Zebra Danio
Brachydanio rerio
NP_956078
307
34683
R256
S
T
S
T
E
A
E
R
E
S
N
A
G
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498165
467
53727
V430
G
K
M
A
D
G
P
V
L
P
D
E
M
Y
T
Sea Urchin
Strong. purpuratus
XP_001197735
355
39844
E312
M
E
G
G
E
A
D
E
E
E
G
S
G
A
A
Poplar Tree
Populus trichocarpa
XP_002307158
149
16865
A113
G
E
N
E
A
D
L
A
D
G
E
T
F
K
A
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196449
150
17037
S113
S
E
M
Q
E
T
G
S
E
D
S
E
K
V
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
88.1
89.5
N.A.
87.3
87.7
N.A.
74.4
68.9
63.4
61.5
N.A.
N.A.
N.A.
23.9
41.6
Protein Similarity:
100
99.6
89.8
93.3
N.A.
91.2
91.9
N.A.
82.1
82.2
77.4
73.9
N.A.
N.A.
N.A.
37.2
59.1
P-Site Identity:
100
100
100
66.6
N.A.
46.6
6.6
N.A.
53.3
26.6
6.6
13.3
N.A.
N.A.
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
73.3
N.A.
66.6
13.3
N.A.
60
53.3
20
33.3
N.A.
N.A.
N.A.
26.6
26.6
Percent
Protein Identity:
28.4
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
40
N.A.
N.A.
40.3
N.A.
N.A.
P-Site Identity:
20
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
36
29
15
15
43
0
15
0
15
0
8
0
8
15
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
29
0
8
8
8
8
8
0
29
8
8
0
0
0
0
% D
% Glu:
0
36
8
43
29
15
50
22
43
29
72
65
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
15
0
8
15
0
8
8
8
0
8
8
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
15
50
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
8
43
0
0
% I
% Lys:
0
8
0
0
22
0
0
0
0
0
0
0
8
8
0
% K
% Leu:
0
0
0
8
0
0
8
0
8
0
0
0
0
8
0
% L
% Met:
8
0
15
0
0
0
0
0
8
0
0
8
8
0
0
% M
% Asn:
8
0
8
0
0
0
8
0
0
0
8
0
0
0
8
% N
% Pro:
8
8
8
0
8
0
8
0
0
8
0
0
0
0
15
% P
% Gln:
0
0
0
8
15
8
0
8
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% R
% Ser:
15
0
8
0
0
8
0
8
0
8
8
8
0
0
0
% S
% Thr:
22
15
15
8
8
15
8
22
0
8
0
8
0
0
15
% T
% Val:
0
0
0
0
0
0
0
8
8
22
0
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
15
58
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _