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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EAPP
All Species:
12.12
Human Site:
Y158
Identified Species:
20.51
UniProt:
Q56P03
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q56P03
NP_060923.2
285
32734
Y158
V
D
A
Q
R
R
G
Y
H
G
L
G
P
Q
R
Chimpanzee
Pan troglodytes
XP_509897
285
32735
Y158
V
D
A
Q
R
R
G
Y
H
G
L
G
P
Q
R
Rhesus Macaque
Macaca mulatta
XP_001104634
296
33316
Y169
V
D
A
Q
R
R
G
Y
H
G
L
G
L
Q
R
Dog
Lupus familis
XP_850430
286
32978
H159
D
A
Q
R
R
G
Y
H
G
F
G
I
Q
R
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5BU09
281
32475
R154
A
W
V
D
A
K
R
R
G
Y
H
A
F
G
L
Rat
Rattus norvegicus
NP_001128459
280
32140
G154
W
V
D
A
K
R
R
G
Y
H
A
F
G
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512221
286
33024
Y159
V
D
A
Q
R
M
G
Y
H
G
L
R
V
Q
G
Chicken
Gallus gallus
XP_421235
287
33535
R160
W
V
D
S
Q
R
R
R
Y
R
N
Q
R
R
V
Frog
Xenopus laevis
NP_001085682
293
33892
K167
R
R
Y
W
N
M
R
K
P
K
Q
T
H
P
Q
Zebra Danio
Brachydanio rerio
NP_956078
307
34683
P166
K
A
Y
R
S
Q
R
P
L
P
P
S
A
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_498165
467
53727
E340
D
Q
E
D
E
D
N
E
K
W
V
K
E
H
R
Sea Urchin
Strong. purpuratus
XP_001197735
355
39844
P222
P
A
Q
P
S
Q
T
P
K
P
D
K
V
T
G
Poplar Tree
Populus trichocarpa
XP_002307158
149
16865
P23
E
I
D
Y
S
V
K
P
E
F
Y
D
P
E
L
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196449
150
17037
P23
E
V
D
Y
S
I
K
P
E
F
Y
D
S
D
I
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
88.1
89.5
N.A.
87.3
87.7
N.A.
74.4
68.9
63.4
61.5
N.A.
N.A.
N.A.
23.9
41.6
Protein Similarity:
100
99.6
89.8
93.3
N.A.
91.2
91.9
N.A.
82.1
82.2
77.4
73.9
N.A.
N.A.
N.A.
37.2
59.1
P-Site Identity:
100
100
93.3
6.6
N.A.
0
6.6
N.A.
73.3
6.6
0
6.6
N.A.
N.A.
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
26.6
N.A.
6.6
26.6
N.A.
73.3
26.6
6.6
20
N.A.
N.A.
N.A.
13.3
6.6
Percent
Protein Identity:
28.4
N.A.
N.A.
27.7
N.A.
N.A.
Protein Similarity:
40
N.A.
N.A.
40.3
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
29
8
8
0
0
0
0
0
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
15
29
29
15
0
8
0
0
0
0
8
15
0
8
0
% D
% Glu:
15
0
8
0
8
0
0
8
15
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
22
0
8
8
0
0
% F
% Gly:
0
0
0
0
0
8
29
8
15
29
8
22
8
8
15
% G
% His:
0
0
0
0
0
0
0
8
29
8
8
0
8
8
0
% H
% Ile:
0
8
0
0
0
8
0
0
0
0
0
8
0
0
8
% I
% Lys:
8
0
0
0
8
8
15
8
15
8
0
15
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
8
0
29
0
8
8
15
% L
% Met:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
8
0
0
0
8
0
0
8
0
% N
% Pro:
8
0
0
8
0
0
0
29
8
15
8
0
22
8
8
% P
% Gln:
0
8
15
29
8
15
0
0
0
0
8
8
8
29
15
% Q
% Arg:
8
8
0
15
36
36
36
15
0
8
0
8
8
15
36
% R
% Ser:
0
0
0
8
29
0
0
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
8
0
8
0
% T
% Val:
29
22
8
0
0
8
0
0
0
0
8
0
15
0
8
% V
% Trp:
15
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
15
15
0
0
8
29
15
8
15
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _