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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 20.3
Human Site: S53 Identified Species: 29.78
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 S53 S P S L L N D S A K P Y S A H
Chimpanzee Pan troglodytes XP_001136622 741 82148 S53 S P S L L N D S A K P Y S A H
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 S53 S P S L L N D S A K P Y S G H
Dog Lupus familis XP_543150 987 105833 S299 S P S L L N D S A K P Y A G H
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 S43 L M Q R M T S S S S S P S L L
Rat Rattus norvegicus XP_002724835 883 95283 S195 S P S L L N D S A K P Y T G H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 A60 V N G F G S P A E A K Y P M M
Chicken Gallus gallus XP_417120 757 83269 L67 S L Q A E G N L V P G M D G G
Frog Xenopus laevis NP_001128699 631 68072
Zebra Danio Brachydanio rerio XP_002666687 799 86684 P115 E G Q L L S I P G M E G G A L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 L59 N G F S L L N L D S P L N K K
Honey Bee Apis mellifera XP_623553 607 67474
Nematode Worm Caenorhab. elegans P34653 632 71182
Sea Urchin Strong. purpuratus XP_796055 760 83393 S63 G G Q K R D E S P S F Q P G Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 P31 K K E K E G C P F K H S D N T
Red Bread Mold Neurospora crassa Q7SDP4 656 73993 S8 M A A T R Y N S G D L R R Q V
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 93.3 86.6 N.A. 13.3 86.6 N.A. 6.6 6.6 0 20 N.A. 13.3 0 0 6.6
P-Site Similarity: 100 100 93.3 93.3 N.A. 26.6 93.3 N.A. 20 13.3 0 26.6 N.A. 33.3 0 0 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 6.6
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 7 7 0 0 0 7 32 7 0 0 7 19 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 32 0 7 7 0 0 13 0 0 % D
% Glu: 7 0 7 0 13 0 7 0 7 0 7 0 0 0 0 % E
% Phe: 0 0 7 7 0 0 0 0 7 0 7 0 0 0 0 % F
% Gly: 7 19 7 0 7 13 0 0 13 0 7 7 7 32 7 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 32 % H
% Ile: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % I
% Lys: 7 7 0 13 0 0 0 0 0 38 7 0 0 7 7 % K
% Leu: 7 7 0 38 44 7 0 13 0 0 7 7 0 7 13 % L
% Met: 7 7 0 0 7 0 0 0 0 7 0 7 0 7 7 % M
% Asn: 7 7 0 0 0 32 19 0 0 0 0 0 7 7 0 % N
% Pro: 0 32 0 0 0 0 7 13 7 7 38 7 13 0 0 % P
% Gln: 0 0 25 0 0 0 0 0 0 0 0 7 0 7 7 % Q
% Arg: 0 0 0 7 13 0 0 0 0 0 0 7 7 0 0 % R
% Ser: 38 0 32 7 0 13 7 50 7 19 7 7 25 0 0 % S
% Thr: 0 0 0 7 0 7 0 0 0 0 0 0 7 0 7 % T
% Val: 7 0 0 0 0 0 0 0 7 0 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 0 0 0 0 38 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _