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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAN3 All Species: 20.91
Human Site: T32 Identified Species: 30.67
UniProt: Q58A45 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58A45 NP_787050.4 741 82181 T32 G F G S P V E T K Y P L M Q R
Chimpanzee Pan troglodytes XP_001136622 741 82148 T32 G F G S P V E T K Y P L M Q R
Rhesus Macaque Macaca mulatta XP_001097210 741 82134 T32 G F G S P V E T K Y P L M Q R
Dog Lupus familis XP_543150 987 105833 T278 G F G S P V E T K Y P L M Q R
Cat Felis silvestris
Mouse Mus musculus Q640Q5 691 76362 G22 Y F S T S F I G V N G F G S P
Rat Rattus norvegicus XP_002724835 883 95283 T174 G F G S P V E T K Y P L M Q R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519591 717 78728 S39 D G G A L A D S S L T D S Y F
Chicken Gallus gallus XP_417120 757 83269 S46 L N E H T R C S V E N H L S K
Frog Xenopus laevis NP_001128699 631 68072
Zebra Danio Brachydanio rerio XP_002666687 799 86684 V94 G G S A A S G V P A S V S K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_728797 788 85176 N38 S K L A T Y M N R Q N V A T P
Honey Bee Apis mellifera XP_623553 607 67474
Nematode Worm Caenorhab. elegans P34653 632 71182
Sea Urchin Strong. purpuratus XP_796055 760 83393 S42 R S H S V G S S L S T Y T G S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P36102 679 76436 K10 K I N P D W A K D I P C R N I
Red Bread Mold Neurospora crassa Q7SDP4 656 73993
Conservation
Percent
Protein Identity: 100 99.8 99.7 74.4 N.A. 90.1 82.2 N.A. 80.8 78.3 58.4 68.2 N.A. 38.5 41.8 31.9 49.3
Protein Similarity: 100 100 99.8 74.7 N.A. 90.9 83 N.A. 86 84.1 64 75 N.A. 55.7 59.6 49.5 62.6
P-Site Identity: 100 100 100 100 N.A. 6.6 100 N.A. 6.6 0 0 6.6 N.A. 0 0 0 6.6
P-Site Similarity: 100 100 100 100 N.A. 13.3 100 N.A. 26.6 20 0 33.3 N.A. 20 0 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 21.7 28
Protein Similarity: N.A. N.A. N.A. N.A. 42.1 45.2
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 0
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 19 7 7 7 0 0 7 0 0 7 0 0 % A
% Cys: 0 0 0 0 0 0 7 0 0 0 0 7 0 0 0 % C
% Asp: 7 0 0 0 7 0 7 0 7 0 0 7 0 0 0 % D
% Glu: 0 0 7 0 0 0 32 0 0 7 0 0 0 0 0 % E
% Phe: 0 38 0 0 0 7 0 0 0 0 0 7 0 0 7 % F
% Gly: 38 13 38 0 0 7 7 7 0 0 7 0 7 7 0 % G
% His: 0 0 7 7 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 7 0 0 0 0 7 0 0 7 0 0 0 0 7 % I
% Lys: 7 7 0 0 0 0 0 7 32 0 0 0 0 7 13 % K
% Leu: 7 0 7 0 7 0 0 0 7 7 0 32 7 0 0 % L
% Met: 0 0 0 0 0 0 7 0 0 0 0 0 32 0 0 % M
% Asn: 0 7 7 0 0 0 0 7 0 7 13 0 0 7 0 % N
% Pro: 0 0 0 7 32 0 0 0 7 0 38 0 0 0 13 % P
% Gln: 0 0 0 0 0 0 0 0 0 7 0 0 0 32 0 % Q
% Arg: 7 0 0 0 0 7 0 0 7 0 0 0 7 0 32 % R
% Ser: 7 7 13 38 7 7 7 19 7 7 7 0 13 13 7 % S
% Thr: 0 0 0 7 13 0 0 32 0 0 13 0 7 7 0 % T
% Val: 0 0 0 0 7 32 0 7 13 0 0 13 0 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 7 0 0 0 32 0 7 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _