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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK2
All Species:
20.61
Human Site:
S2041
Identified Species:
41.21
UniProt:
Q58EX2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX2
NP_001138424.1
2170
239121
S2041
N
D
L
I
P
A
E
S
S
S
L
T
E
K
P
Chimpanzee
Pan troglodytes
XP_511658
2191
240641
S2060
N
D
L
I
P
A
E
S
S
S
L
T
E
K
P
Rhesus Macaque
Macaca mulatta
XP_001087501
2062
226261
S1932
D
L
I
P
A
E
S
S
S
L
T
E
K
P
S
Dog
Lupus familis
XP_540402
2230
245157
S2099
N
D
L
I
P
A
E
S
S
S
L
T
E
K
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6V4S5
2176
239883
S2045
N
D
L
I
P
A
E
S
S
S
L
T
E
K
P
Rat
Rattus norvegicus
Q8VHZ8
2013
222236
G1882
P
P
K
P
Q
D
G
G
R
V
V
N
M
A
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
P2000
K
K
N
G
T
R
S
P
P
R
P
S
P
G
G
Chicken
Gallus gallus
Q8AV57
2177
239133
S2046
N
D
L
I
P
A
E
S
S
S
L
T
E
K
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
P2093
K
S
T
S
R
P
P
P
G
V
H
L
G
K
S
Honey Bee
Apis mellifera
XP_623565
2176
242722
P2045
A
R
K
S
M
H
P
P
P
P
T
M
L
G
K
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
D2130
N
M
Y
G
L
A
T
D
V
I
P
P
L
P
N
Sea Urchin
Strong. purpuratus
XP_001186318
1662
181499
T1532
L
A
T
A
T
A
A
T
S
P
H
L
T
S
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
92.6
91.3
N.A.
94.5
20.6
N.A.
58
86.9
N.A.
N.A.
N.A.
36.8
36.1
28.4
31.6
Protein Similarity:
100
96.9
93.5
94.1
N.A.
97.4
37.8
N.A.
74.9
92.9
N.A.
N.A.
N.A.
53.2
55.1
45.5
45.9
P-Site Identity:
100
100
13.3
100
N.A.
100
0
N.A.
0
100
N.A.
N.A.
N.A.
6.6
0
13.3
13.3
P-Site Similarity:
100
100
33.3
100
N.A.
100
6.6
N.A.
6.6
100
N.A.
N.A.
N.A.
6.6
0
13.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
9
59
9
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
42
0
0
0
9
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
9
42
0
0
0
0
9
42
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
0
0
0
17
0
0
9
9
9
0
0
0
9
17
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
17
0
0
0
0
% H
% Ile:
0
0
9
42
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
17
9
17
0
0
0
0
0
0
0
0
0
9
50
9
% K
% Leu:
9
9
42
0
9
0
0
0
0
9
42
17
17
0
0
% L
% Met:
0
9
0
0
9
0
0
0
0
0
0
9
9
0
0
% M
% Asn:
50
0
9
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
9
9
0
17
42
9
17
25
17
17
17
9
9
17
42
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
9
0
0
9
9
0
0
0
0
0
% R
% Ser:
0
9
0
17
0
0
17
50
59
42
0
9
0
9
17
% S
% Thr:
0
0
17
0
17
0
9
9
0
0
17
42
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
17
9
0
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _