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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK2
All Species:
21.82
Human Site:
S2057
Identified Species:
43.64
UniProt:
Q58EX2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX2
NP_001138424.1
2170
239121
S2057
E
I
S
D
S
Q
G
S
D
S
E
Y
E
V
D
Chimpanzee
Pan troglodytes
XP_511658
2191
240641
S2076
E
I
S
D
S
Q
G
S
D
S
E
Y
E
V
D
Rhesus Macaque
Macaca mulatta
XP_001087501
2062
226261
D1948
I
S
D
S
Q
G
S
D
S
E
Y
E
V
D
S
Dog
Lupus familis
XP_540402
2230
245157
S2115
E
I
S
D
S
Q
G
S
D
S
E
Y
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q6V4S5
2176
239883
S2061
E
I
S
D
S
Q
G
S
D
S
E
Y
E
V
D
Rat
Rattus norvegicus
Q8VHZ8
2013
222236
L1898
K
A
H
R
P
G
D
L
I
H
L
P
P
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
C2016
H
Y
S
D
E
D
I
C
N
K
Y
N
G
A
V
Chicken
Gallus gallus
Q8AV57
2177
239133
S2062
E
V
S
D
S
Q
G
S
D
S
E
Y
E
V
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
V2109
P
R
P
S
P
A
S
V
A
Y
H
S
D
E
E
Honey Bee
Apis mellifera
XP_623565
2176
242722
S2061
P
P
R
P
S
P
A
S
V
A
Y
H
S
D
E
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
E2146
G
P
P
H
T
S
V
E
A
M
Q
K
L
S
A
Sea Urchin
Strong. purpuratus
XP_001186318
1662
181499
T1548
A
T
T
E
A
G
G
T
N
A
A
Q
K
N
F
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
92.6
91.3
N.A.
94.5
20.6
N.A.
58
86.9
N.A.
N.A.
N.A.
36.8
36.1
28.4
31.6
Protein Similarity:
100
96.9
93.5
94.1
N.A.
97.4
37.8
N.A.
74.9
92.9
N.A.
N.A.
N.A.
53.2
55.1
45.5
45.9
P-Site Identity:
100
100
0
93.3
N.A.
100
0
N.A.
13.3
93.3
N.A.
N.A.
N.A.
0
13.3
0
6.6
P-Site Similarity:
100
100
0
93.3
N.A.
100
6.6
N.A.
20
100
N.A.
N.A.
N.A.
13.3
33.3
13.3
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
0
9
9
9
0
17
17
9
0
0
17
9
% A
% Cys:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
50
0
9
9
9
42
0
0
0
9
17
42
% D
% Glu:
42
0
0
9
9
0
0
9
0
9
42
9
42
9
17
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% F
% Gly:
9
0
0
0
0
25
50
0
0
0
0
0
9
0
0
% G
% His:
9
0
9
9
0
0
0
0
0
9
9
9
0
0
0
% H
% Ile:
9
34
0
0
0
0
9
0
9
0
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
0
0
0
0
9
0
9
9
0
0
% K
% Leu:
0
0
0
0
0
0
0
9
0
0
9
0
9
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
0
0
9
0
9
0
% N
% Pro:
17
17
17
9
17
9
0
0
0
0
0
9
9
0
0
% P
% Gln:
0
0
0
0
9
42
0
0
0
0
9
9
0
0
0
% Q
% Arg:
0
9
9
9
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
9
50
17
50
9
17
50
9
42
0
9
9
9
9
% S
% Thr:
0
9
9
0
9
0
0
9
0
0
0
0
0
0
0
% T
% Val:
0
9
0
0
0
0
9
9
9
0
0
0
9
34
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
0
0
9
25
42
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _