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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK2
All Species:
20.61
Human Site:
S2105
Identified Species:
41.21
UniProt:
Q58EX2
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX2
NP_001138424.1
2170
239121
S2105
Q
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
Chimpanzee
Pan troglodytes
XP_511658
2191
240641
S2124
Q
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
Rhesus Macaque
Macaca mulatta
XP_001087501
2062
226261
D1996
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
A
Dog
Lupus familis
XP_540402
2230
245157
S2163
Q
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
Cat
Felis silvestris
Mouse
Mus musculus
Q6V4S5
2176
239883
S2109
Q
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
Rat
Rattus norvegicus
Q8VHZ8
2013
222236
T1946
R
P
T
V
L
E
P
T
P
M
E
A
S
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
P2064
V
N
H
Y
M
S
D
P
T
Y
Y
N
S
W
K
Chicken
Gallus gallus
Q8AV57
2177
239133
S2110
Q
A
Y
S
Y
T
E
S
D
S
G
E
P
D
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
P2157
N
E
S
V
R
S
D
P
H
S
F
V
N
H
Y
Honey Bee
Apis mellifera
XP_623565
2176
242722
P2109
N
E
S
V
Q
S
D
P
H
S
F
V
N
H
Y
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S2194
S
D
L
Y
A
T
R
S
E
Y
G
R
V
E
Y
Sea Urchin
Strong. purpuratus
XP_001186318
1662
181499
K1596
Y
V
D
R
K
V
H
K
R
M
T
P
D
E
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
92.6
91.3
N.A.
94.5
20.6
N.A.
58
86.9
N.A.
N.A.
N.A.
36.8
36.1
28.4
31.6
Protein Similarity:
100
96.9
93.5
94.1
N.A.
97.4
37.8
N.A.
74.9
92.9
N.A.
N.A.
N.A.
53.2
55.1
45.5
45.9
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
0
100
N.A.
N.A.
N.A.
6.6
6.6
20
0
P-Site Similarity:
100
100
0
100
N.A.
100
13.3
N.A.
20
100
N.A.
N.A.
N.A.
26.6
26.6
40
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
42
0
0
9
0
0
0
0
0
0
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
9
9
0
0
0
25
9
42
0
0
0
17
42
0
% D
% Glu:
0
17
0
0
0
17
42
0
9
0
17
42
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
9
50
0
0
0
0
% G
% His:
0
0
9
0
0
0
9
0
17
0
0
0
0
25
42
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
9
0
0
9
0
0
0
0
0
0
9
% K
% Leu:
0
0
9
0
9
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
17
0
0
0
0
0
% M
% Asn:
17
9
0
0
0
0
0
0
0
0
0
9
17
0
0
% N
% Pro:
0
9
0
0
0
0
9
25
9
0
0
17
42
0
0
% P
% Gln:
42
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
0
0
9
9
0
9
0
9
0
0
9
0
0
9
% R
% Ser:
9
0
25
42
0
25
9
50
9
59
0
0
17
9
9
% S
% Thr:
0
0
9
0
9
50
0
9
9
0
9
0
0
0
0
% T
% Val:
9
9
0
25
0
9
0
0
0
0
0
17
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
9
9
42
25
42
0
0
0
0
17
9
0
0
0
25
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _