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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK2
All Species:
22.12
Human Site:
S2118
Identified Species:
44.24
UniProt:
Q58EX2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX2
NP_001138424.1
2170
239121
S2118
D
H
T
T
V
T
N
S
T
S
T
Q
Q
G
S
Chimpanzee
Pan troglodytes
XP_511658
2191
240641
S2137
D
H
A
T
V
T
N
S
T
S
T
Q
Q
G
S
Rhesus Macaque
Macaca mulatta
XP_001087501
2062
226261
T2009
H
A
T
V
T
N
S
T
S
T
Q
Q
G
S
L
Dog
Lupus familis
XP_540402
2230
245157
S2176
D
H
A
T
V
A
N
S
S
S
A
Q
Q
G
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6V4S5
2176
239883
S2122
D
H
V
T
V
P
N
S
N
S
T
Q
Q
G
S
Rat
Rattus norvegicus
Q8VHZ8
2013
222236
E1959
S
S
T
S
S
T
R
E
G
Q
Q
S
W
Q
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
V2077
W
K
R
Q
Q
K
G
V
K
P
P
A
T
Y
R
Chicken
Gallus gallus
Q8AV57
2177
239133
S2123
D
H
T
P
L
S
N
S
T
S
T
Q
Q
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S2170
H
Y
A
N
V
N
D
S
L
R
Q
S
W
K
K
Honey Bee
Apis mellifera
XP_623565
2176
242722
S2122
H
Y
A
N
V
N
D
S
L
R
Q
S
W
K
R
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
S2207
E
Y
R
G
H
I
P
S
S
S
G
G
S
G
A
Sea Urchin
Strong. purpuratus
XP_001186318
1662
181499
D1609
E
R
V
N
G
T
E
D
G
G
F
T
S
F
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
92.6
91.3
N.A.
94.5
20.6
N.A.
58
86.9
N.A.
N.A.
N.A.
36.8
36.1
28.4
31.6
Protein Similarity:
100
96.9
93.5
94.1
N.A.
97.4
37.8
N.A.
74.9
92.9
N.A.
N.A.
N.A.
53.2
55.1
45.5
45.9
P-Site Identity:
100
93.3
13.3
73.3
N.A.
80
13.3
N.A.
0
80
N.A.
N.A.
N.A.
13.3
13.3
20
6.6
P-Site Similarity:
100
93.3
40
80
N.A.
80
20
N.A.
0
93.3
N.A.
N.A.
N.A.
26.6
26.6
46.6
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
34
0
0
9
0
0
0
0
9
9
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
42
0
0
0
0
0
17
9
0
0
0
0
0
0
0
% D
% Glu:
17
0
0
0
0
0
9
9
0
0
0
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% F
% Gly:
0
0
0
9
9
0
9
0
17
9
9
9
9
50
0
% G
% His:
25
42
0
0
9
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
0
9
0
0
9
0
0
0
0
17
9
% K
% Leu:
0
0
0
0
9
0
0
0
17
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
25
0
25
42
0
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
9
9
0
0
9
9
0
0
0
0
% P
% Gln:
0
0
0
9
9
0
0
0
0
9
34
50
42
9
9
% Q
% Arg:
0
9
17
0
0
0
9
0
0
17
0
0
0
0
17
% R
% Ser:
9
9
0
9
9
9
9
67
25
50
0
25
17
9
42
% S
% Thr:
0
0
34
34
9
34
0
9
25
9
34
9
9
0
0
% T
% Val:
0
0
17
9
50
0
0
9
0
0
0
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
25
0
0
% W
% Tyr:
0
25
0
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _