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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SDK2 All Species: 12.42
Human Site: T2114 Identified Species: 24.85
UniProt: Q58EX2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58EX2 NP_001138424.1 2170 239121 T2114 S G E P D H T T V T N S T S T
Chimpanzee Pan troglodytes XP_511658 2191 240641 T2133 S G E P D H A T V T N S T S T
Rhesus Macaque Macaca mulatta XP_001087501 2062 226261 V2005 G E P D H A T V T N S T S T Q
Dog Lupus familis XP_540402 2230 245157 T2172 S G E P D H A T V A N S S S A
Cat Felis silvestris
Mouse Mus musculus Q6V4S5 2176 239883 T2118 S G E P D H V T V P N S N S T
Rat Rattus norvegicus Q8VHZ8 2013 222236 S1955 M E A S S S T S S T R E G Q Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513017 2131 235273 Q2073 Y Y N S W K R Q Q K G V K P P
Chicken Gallus gallus Q8AV57 2177 239133 P2119 S G E P D H T P L S N S T S T
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O97394 2224 246236 N2166 S F V N H Y A N V N D S L R Q
Honey Bee Apis mellifera XP_623565 2176 242722 N2118 S F V N H Y A N V N D S L R Q
Nematode Worm Caenorhab. elegans Q9N3X8 2325 259146 G2203 Y G R V E Y R G H I P S S S G
Sea Urchin Strong. purpuratus XP_001186318 1662 181499 N1605 M T P D E R V N G T E D G G F
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.2 92.6 91.3 N.A. 94.5 20.6 N.A. 58 86.9 N.A. N.A. N.A. 36.8 36.1 28.4 31.6
Protein Similarity: 100 96.9 93.5 94.1 N.A. 97.4 37.8 N.A. 74.9 92.9 N.A. N.A. N.A. 53.2 55.1 45.5 45.9
P-Site Identity: 100 93.3 6.6 73.3 N.A. 80 13.3 N.A. 0 80 N.A. N.A. N.A. 20 20 20 6.6
P-Site Similarity: 100 93.3 33.3 80 N.A. 80 20 N.A. 0 93.3 N.A. N.A. N.A. 33.3 33.3 40 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 0 0 9 34 0 0 9 0 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 42 0 0 0 0 0 17 9 0 0 0 % D
% Glu: 0 17 42 0 17 0 0 0 0 0 9 9 0 0 0 % E
% Phe: 0 17 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 9 50 0 0 0 0 0 9 9 0 9 0 17 9 9 % G
% His: 0 0 0 0 25 42 0 0 9 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 9 0 0 9 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 9 0 0 0 17 0 0 % L
% Met: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 9 17 0 0 0 25 0 25 42 0 9 0 0 % N
% Pro: 0 0 17 42 0 0 0 9 0 9 9 0 0 9 9 % P
% Gln: 0 0 0 0 0 0 0 9 9 0 0 0 0 9 34 % Q
% Arg: 0 0 9 0 0 9 17 0 0 0 9 0 0 17 0 % R
% Ser: 59 0 0 17 9 9 0 9 9 9 9 67 25 50 0 % S
% Thr: 0 9 0 0 0 0 34 34 9 34 0 9 25 9 34 % T
% Val: 0 0 17 9 0 0 17 9 50 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 9 0 0 0 25 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _