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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SDK2
All Species:
21.21
Human Site:
Y2100
Identified Species:
42.42
UniProt:
Q58EX2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX2
NP_001138424.1
2170
239121
Y2100
G
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
Chimpanzee
Pan troglodytes
XP_511658
2191
240641
Y2119
G
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
Rhesus Macaque
Macaca mulatta
XP_001087501
2062
226261
S1991
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
G
Dog
Lupus familis
XP_540402
2230
245157
Y2158
G
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
Cat
Felis silvestris
Mouse
Mus musculus
Q6V4S5
2176
239883
Y2104
G
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
Rat
Rattus norvegicus
Q8VHZ8
2013
222236
T1941
S
R
T
L
K
R
P
T
V
L
E
P
T
P
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513017
2131
235273
H2059
P
K
H
S
F
V
N
H
Y
M
S
D
P
T
Y
Chicken
Gallus gallus
Q8AV57
2177
239133
Y2105
G
I
S
R
A
Q
A
Y
S
Y
T
E
S
D
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O97394
2224
246236
S2152
H
S
E
S
E
N
E
S
V
R
S
D
P
H
S
Honey Bee
Apis mellifera
XP_623565
2176
242722
S2104
G
S
E
S
E
N
E
S
V
Q
S
D
P
H
S
Nematode Worm
Caenorhab. elegans
Q9N3X8
2325
259146
L2189
Y
M
P
T
R
S
D
L
Y
A
T
R
S
E
Y
Sea Urchin
Strong. purpuratus
XP_001186318
1662
181499
D1591
G
R
S
R
L
Y
V
D
R
K
V
H
K
R
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.2
92.6
91.3
N.A.
94.5
20.6
N.A.
58
86.9
N.A.
N.A.
N.A.
36.8
36.1
28.4
31.6
Protein Similarity:
100
96.9
93.5
94.1
N.A.
97.4
37.8
N.A.
74.9
92.9
N.A.
N.A.
N.A.
53.2
55.1
45.5
45.9
P-Site Identity:
100
100
0
100
N.A.
100
0
N.A.
0
100
N.A.
N.A.
N.A.
6.6
13.3
13.3
20
P-Site Similarity:
100
100
0
100
N.A.
100
20
N.A.
20
100
N.A.
N.A.
N.A.
20
26.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
42
9
42
0
0
9
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
9
9
0
0
0
25
9
42
0
% D
% Glu:
0
0
17
0
17
0
17
0
0
0
17
42
0
9
0
% E
% Phe:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
59
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
9
0
9
0
0
0
0
9
0
0
0
9
0
17
0
% H
% Ile:
9
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
0
0
9
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
0
0
9
9
0
0
9
0
9
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
9
0
0
0
0
17
% M
% Asn:
0
0
0
0
0
17
9
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
9
0
0
0
9
0
0
0
0
9
25
9
0
% P
% Gln:
0
0
0
0
9
42
0
0
0
9
0
0
0
0
0
% Q
% Arg:
0
17
9
50
9
9
0
0
9
9
0
9
0
9
0
% R
% Ser:
9
25
50
25
0
9
0
25
42
0
25
9
50
9
59
% S
% Thr:
0
0
9
9
0
0
0
9
0
9
50
0
9
9
0
% T
% Val:
0
0
0
0
0
9
9
0
25
0
9
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
9
9
42
25
42
0
0
0
0
17
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _