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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG4
All Species:
6.06
Human Site:
S89
Identified Species:
13.33
UniProt:
Q58EX7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX7
NP_001123199.1
1191
130803
S89
A
Q
R
G
T
V
E
S
S
S
V
L
S
E
G
Chimpanzee
Pan troglodytes
XP_526816
1617
177550
S268
P
A
P
V
T
M
E
S
G
R
E
Y
V
S
S
Rhesus Macaque
Macaca mulatta
XP_001087633
1210
132988
S89
P
H
R
G
K
V
E
S
S
S
V
L
S
E
G
Dog
Lupus familis
XP_546879
1286
140661
G171
G
Q
G
C
T
L
E
G
S
S
L
R
L
D
E
Cat
Felis silvestris
Mouse
Mus musculus
Q3UPH7
1517
165114
G240
A
P
A
E
G
P
E
G
E
Y
V
E
L
L
E
Rat
Rattus norvegicus
Q63406
1149
129391
I95
G
Q
D
G
S
P
V
I
T
F
P
D
Y
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517639
1384
151393
R134
L
V
P
F
L
R
R
R
P
R
L
V
L
T
C
Chicken
Gallus gallus
XP_414038
1260
141915
R87
A
V
A
I
I
T
T
R
N
T
A
W
L
N
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693663
1625
182480
V316
L
H
K
P
Q
T
P
V
S
T
Q
L
K
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996017
1428
157695
S132
A
G
E
E
L
L
T
S
H
S
E
A
K
M
R
Honey Bee
Apis mellifera
XP_394195
1121
125609
A91
K
S
S
P
R
R
R
A
D
G
R
R
N
S
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
93.8
75.8
N.A.
26.2
23.1
N.A.
45.7
32.2
N.A.
33.6
N.A.
28.3
27.9
N.A.
N.A.
Protein Similarity:
100
40.2
94.9
81.6
N.A.
39.8
41.3
N.A.
56.1
47.3
N.A.
47.6
N.A.
42.6
45
N.A.
N.A.
P-Site Identity:
100
20
80
33.3
N.A.
20
13.3
N.A.
0
6.6
N.A.
13.3
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
26.6
80
53.3
N.A.
20
26.6
N.A.
13.3
20
N.A.
26.6
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
19
0
0
0
0
10
0
0
10
10
0
0
10
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
10
0
0
0
0
0
10
0
0
10
0
10
0
% D
% Glu:
0
0
10
19
0
0
46
0
10
0
19
10
0
19
19
% E
% Phe:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
19
10
10
28
10
0
0
19
10
10
0
0
0
0
19
% G
% His:
0
19
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
10
10
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
10
0
10
0
10
0
0
0
0
0
0
0
19
0
10
% K
% Leu:
19
0
0
0
19
19
0
0
0
0
19
28
37
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% N
% Pro:
19
10
19
19
0
19
10
0
10
0
10
0
0
10
10
% P
% Gln:
0
28
0
0
10
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
19
0
10
19
19
19
0
19
10
19
0
0
10
% R
% Ser:
0
10
10
0
10
0
0
37
37
37
0
0
19
19
19
% S
% Thr:
0
0
0
0
28
19
19
0
10
19
0
0
0
19
0
% T
% Val:
0
19
0
10
0
19
10
10
0
0
28
10
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
10
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _