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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLEKHG4
All Species:
4.85
Human Site:
S94
Identified Species:
10.67
UniProt:
Q58EX7
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58EX7
NP_001123199.1
1191
130803
S94
V
E
S
S
S
V
L
S
E
G
P
G
P
S
G
Chimpanzee
Pan troglodytes
XP_526816
1617
177550
V273
M
E
S
G
R
E
Y
V
S
S
G
D
G
P
V
Rhesus Macaque
Macaca mulatta
XP_001087633
1210
132988
S94
V
E
S
S
S
V
L
S
E
G
P
G
P
S
G
Dog
Lupus familis
XP_546879
1286
140661
L176
L
E
G
S
S
L
R
L
D
E
P
I
P
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q3UPH7
1517
165114
L245
P
E
G
E
Y
V
E
L
L
E
V
T
L
P
V
Rat
Rattus norvegicus
Q63406
1149
129391
Y100
P
V
I
T
F
P
D
Y
P
A
F
S
E
I
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517639
1384
151393
L139
R
R
R
P
R
L
V
L
T
C
L
A
P
S
G
Chicken
Gallus gallus
XP_414038
1260
141915
L92
T
T
R
N
T
A
W
L
N
P
H
C
N
T
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_693663
1625
182480
K321
T
P
V
S
T
Q
L
K
T
K
P
D
E
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996017
1428
157695
K137
L
T
S
H
S
E
A
K
M
R
S
N
S
V
G
Honey Bee
Apis mellifera
XP_394195
1121
125609
N96
R
R
A
D
G
R
R
N
S
S
F
E
T
R
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
28
93.8
75.8
N.A.
26.2
23.1
N.A.
45.7
32.2
N.A.
33.6
N.A.
28.3
27.9
N.A.
N.A.
Protein Similarity:
100
40.2
94.9
81.6
N.A.
39.8
41.3
N.A.
56.1
47.3
N.A.
47.6
N.A.
42.6
45
N.A.
N.A.
P-Site Identity:
100
13.3
100
46.6
N.A.
13.3
0
N.A.
20
0
N.A.
26.6
N.A.
20
0
N.A.
N.A.
P-Site Similarity:
100
20
100
66.6
N.A.
13.3
6.6
N.A.
33.3
20
N.A.
33.3
N.A.
26.6
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
10
10
0
0
10
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% C
% Asp:
0
0
0
10
0
0
10
0
10
0
0
19
0
0
0
% D
% Glu:
0
46
0
10
0
19
10
0
19
19
0
10
19
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
19
0
0
0
0
% F
% Gly:
0
0
19
10
10
0
0
0
0
19
10
19
10
0
46
% G
% His:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
10
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
19
0
10
0
0
0
0
0
% K
% Leu:
19
0
0
0
0
19
28
37
10
0
10
0
10
0
10
% L
% Met:
10
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
0
0
10
10
0
0
10
10
0
10
% N
% Pro:
19
10
0
10
0
10
0
0
10
10
37
0
37
19
10
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Q
% Arg:
19
19
19
0
19
10
19
0
0
10
0
0
0
10
0
% R
% Ser:
0
0
37
37
37
0
0
19
19
19
10
10
10
46
0
% S
% Thr:
19
19
0
10
19
0
0
0
19
0
0
10
10
10
10
% T
% Val:
19
10
10
0
0
28
10
10
0
0
10
0
0
10
19
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
10
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _