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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90B2P
All Species:
23.64
Human Site:
S23
Identified Species:
40
UniProt:
Q58FF3
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FF3
NP_003290
399
45859
S23
C
K
S
F
S
K
E
S
D
D
P
V
A
C
I
Chimpanzee
Pan troglodytes
XP_001158554
792
91152
S366
Y
K
S
F
S
K
E
S
D
D
P
M
A
Y
I
Rhesus Macaque
Macaca mulatta
XP_001095189
804
92594
S366
Y
K
S
F
S
K
E
S
D
D
P
M
A
Y
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P08113
802
92457
S366
Y
K
S
F
S
K
E
S
D
D
P
M
A
Y
I
Rat
Rattus norvegicus
Q66HD0
804
92752
S366
Y
K
S
F
S
K
E
S
D
D
P
M
A
Y
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507634
816
93562
S382
Y
K
S
F
S
K
E
S
D
D
P
M
A
F
I
Chicken
Gallus gallus
P08110
795
91537
H365
Y
K
T
F
S
K
E
H
D
D
P
M
A
Y
I
Frog
Xenopus laevis
NP_001083114
805
92996
S365
Y
K
S
F
S
K
E
S
D
D
P
M
A
H
I
Zebra Danio
Brachydanio rerio
Q90474
725
83300
N311
E
F
Y
K
S
L
S
N
D
W
E
D
H
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
N303
E
F
Y
K
S
L
T
N
D
W
E
D
H
L
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
N289
E
F
Y
K
S
L
S
N
D
W
E
D
H
L
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q08277
715
81872
N304
S
F
Y
K
S
L
T
N
D
W
E
D
H
L
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STX5
823
94185
D373
S
L
S
K
D
F
T
D
E
K
P
M
A
W
S
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
N294
A
F
Y
K
S
I
S
N
D
W
E
D
P
L
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
44.6
N.A.
N.A.
43.5
42
N.A.
41.5
41.5
38.5
24.9
N.A.
24.8
N.A.
25.3
N.A.
Protein Similarity:
100
46.5
46.2
N.A.
N.A.
45.7
44.7
N.A.
44.8
45.1
44
35.7
N.A.
37
N.A.
38.8
N.A.
P-Site Identity:
100
80
80
N.A.
N.A.
80
80
N.A.
80
66.6
80
13.3
N.A.
13.3
N.A.
13.3
N.A.
P-Site Similarity:
100
86.6
86.6
N.A.
N.A.
86.6
86.6
N.A.
86.6
80
86.6
20
N.A.
20
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
25.7
N.A.
22.9
25.2
N.A.
Protein Similarity:
N.A.
36.3
N.A.
33
37.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
20
13.3
N.A.
P-Site Similarity:
N.A.
20
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
0
65
0
29
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
0
0
8
93
58
0
36
0
0
0
% D
% Glu:
22
0
0
0
0
0
58
0
8
0
36
0
0
0
0
% E
% Phe:
0
36
0
58
0
8
0
0
0
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
29
8
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
58
% I
% Lys:
0
58
0
43
0
58
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
8
0
0
0
29
0
0
0
0
0
0
0
36
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
36
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
65
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
15
0
58
0
93
0
22
50
0
0
0
0
0
0
8
% S
% Thr:
0
0
8
0
0
0
22
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
36
0
0
0
8
0
% W
% Tyr:
50
0
36
0
0
0
0
0
0
0
0
0
0
36
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _