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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90B2P
All Species:
29.7
Human Site:
T125
Identified Species:
50.26
UniProt:
Q58FF3
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FF3
NP_003290
399
45859
T125
R
K
K
L
V
H
K
T
L
D
M
I
K
K
I
Chimpanzee
Pan troglodytes
XP_001158554
792
91152
T468
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Rhesus Macaque
Macaca mulatta
XP_001095189
804
92594
T468
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P08113
802
92457
T468
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Rat
Rattus norvegicus
Q66HD0
804
92752
T468
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507634
816
93562
T484
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Chicken
Gallus gallus
P08110
795
91537
T467
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Frog
Xenopus laevis
NP_001083114
805
92996
T467
R
K
K
L
V
R
K
T
L
D
M
I
K
K
I
Zebra Danio
Brachydanio rerio
Q90474
725
83300
L414
K
N
L
V
K
K
C
L
D
L
F
T
E
L
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
M406
K
N
L
V
K
K
T
M
E
L
I
E
E
L
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
M392
K
N
L
V
K
K
C
M
E
L
I
D
E
V
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q08277
715
81872
I407
K
N
L
V
K
K
C
I
E
M
F
F
E
I
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STX5
823
94185
V498
H
D
D
E
K
K
D
V
E
K
S
G
E
N
D
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
I397
K
N
I
V
K
K
L
I
E
A
F
N
E
I
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
44.6
N.A.
N.A.
43.5
42
N.A.
41.5
41.5
38.5
24.9
N.A.
24.8
N.A.
25.3
N.A.
Protein Similarity:
100
46.5
46.2
N.A.
N.A.
45.7
44.7
N.A.
44.8
45.1
44
35.7
N.A.
37
N.A.
38.8
N.A.
P-Site Identity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
20
N.A.
26.6
N.A.
26.6
N.A.
Percent
Protein Identity:
N.A.
25.7
N.A.
22.9
25.2
N.A.
Protein Similarity:
N.A.
36.3
N.A.
33
37.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
20
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
29
% A
% Cys:
0
0
0
0
0
0
22
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
0
0
0
8
0
8
58
0
8
0
0
8
% D
% Glu:
0
0
0
8
0
0
0
0
36
0
0
8
43
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
22
8
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% G
% His:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
15
0
0
15
58
0
15
58
% I
% Lys:
36
58
58
0
43
43
58
0
0
8
0
0
58
58
0
% K
% Leu:
0
0
29
58
0
0
8
8
58
22
0
0
0
15
0
% L
% Met:
0
0
0
0
0
0
0
15
0
8
58
0
0
0
0
% M
% Asn:
0
36
0
0
0
0
0
0
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
58
0
0
0
0
50
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
8
58
0
0
0
8
0
0
8
% T
% Val:
0
0
0
36
58
0
0
8
0
0
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _