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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90B2P
All Species:
31.52
Human Site:
Y316
Identified Species:
53.33
UniProt:
Q58FF3
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FF3
NP_003290
399
45859
Y316
G
K
G
I
S
T
N
Y
H
A
S
R
K
K
T
Chimpanzee
Pan troglodytes
XP_001158554
792
91152
Y677
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Rhesus Macaque
Macaca mulatta
XP_001095189
804
92594
Y677
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P08113
802
92457
Y677
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Rat
Rattus norvegicus
Q66HD0
804
92752
Y677
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507634
816
93562
Y693
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Chicken
Gallus gallus
P08110
795
91537
Y676
G
K
D
I
S
T
N
Y
Y
A
S
Q
K
K
T
Frog
Xenopus laevis
NP_001083114
805
92996
Y676
G
K
D
I
S
T
N
Y
Y
S
S
Q
K
K
T
Zebra Danio
Brachydanio rerio
Q90474
725
83300
T622
N
S
T
M
G
Y
M
T
A
K
K
H
L
E
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
A614
T
A
T
M
G
Y
M
A
G
K
K
Q
L
E
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
A599
S
S
T
M
G
Y
M
A
A
K
K
H
L
E
I
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q08277
715
81872
S617
S
S
M
S
A
Y
M
S
S
K
K
T
M
E
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9STX5
823
94185
R703
A
N
K
Q
A
Y
M
R
G
K
R
V
L
E
I
Baker's Yeast
Sacchar. cerevisiae
P15108
705
80881
S604
S
S
M
S
S
Y
M
S
S
K
K
T
F
E
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.7
44.6
N.A.
N.A.
43.5
42
N.A.
41.5
41.5
38.5
24.9
N.A.
24.8
N.A.
25.3
N.A.
Protein Similarity:
100
46.5
46.2
N.A.
N.A.
45.7
44.7
N.A.
44.8
45.1
44
35.7
N.A.
37
N.A.
38.8
N.A.
P-Site Identity:
100
80
80
N.A.
N.A.
80
80
N.A.
80
80
73.3
0
N.A.
0
N.A.
0
N.A.
P-Site Similarity:
100
93.3
93.3
N.A.
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
13.3
N.A.
20
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
25.7
N.A.
22.9
25.2
N.A.
Protein Similarity:
N.A.
36.3
N.A.
33
37.7
N.A.
P-Site Identity:
N.A.
0
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
15
0
0
15
15
50
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
43
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
58
0
8
0
22
0
0
0
15
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
8
0
0
15
0
0
0
% H
% Ile:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
43
% I
% Lys:
0
58
8
0
0
0
0
0
0
43
36
0
58
58
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
29
0
0
% L
% Met:
0
0
15
22
0
0
43
0
0
0
0
0
8
0
0
% M
% Asn:
8
8
0
0
0
0
58
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
0
0
0
58
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
0
0
8
8
0
0
0
% R
% Ser:
22
29
0
15
65
0
0
15
15
8
58
0
0
0
0
% S
% Thr:
8
0
22
0
0
58
0
8
0
0
0
15
0
0
58
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
43
0
58
50
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _