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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AB3P
All Species:
20.61
Human Site:
S429
Identified Species:
37.78
UniProt:
Q58FF7
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FF7
NP_031381
597
68325
S429
E
K
K
K
M
E
E
S
K
E
K
F
E
N
L
Chimpanzee
Pan troglodytes
A5A6K9
733
84754
K565
E
K
K
K
Q
E
E
K
K
T
K
F
E
N
L
Rhesus Macaque
Macaca mulatta
XP_001098219
597
68451
S429
E
K
K
K
M
E
E
S
K
A
K
F
E
N
L
Dog
Lupus familis
XP_532154
636
72879
S468
E
K
K
K
M
E
E
S
K
A
K
F
E
N
L
Cat
Felis silvestris
Mouse
Mus musculus
P11499
724
83307
S556
E
K
K
K
M
E
E
S
K
A
K
F
E
N
L
Rat
Rattus norvegicus
P34058
724
83263
S556
E
K
K
K
M
E
E
S
K
A
K
F
E
N
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518700
789
90657
K644
E
D
E
E
E
K
K
K
M
E
E
S
K
A
K
Chicken
Gallus gallus
Q04619
725
83409
S557
E
K
K
N
M
E
E
S
K
A
K
F
E
T
L
Frog
Xenopus laevis
NP_001086624
722
82939
N554
E
K
K
T
M
E
E
N
K
T
K
F
E
S
L
Zebra Danio
Brachydanio rerio
Q90474
725
83300
L557
E
K
K
K
Q
D
E
L
K
A
K
Y
E
N
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02828
717
81847
D549
E
K
K
K
R
E
E
D
K
A
K
F
E
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q18688
702
80265
D534
E
K
K
K
F
E
E
D
K
V
A
Y
E
N
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P55737
699
80046
L535
E
K
K
K
K
E
E
L
K
E
K
F
E
G
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
69
95.8
83.6
N.A.
78.4
78.8
N.A.
67.5
74.7
73.5
66.3
N.A.
64
N.A.
61.9
N.A.
Protein Similarity:
100
76.2
97.8
86
N.A.
80.3
80.6
N.A.
70.3
79
78.3
75.3
N.A.
73.2
N.A.
73.5
N.A.
P-Site Identity:
100
80
93.3
93.3
N.A.
93.3
93.3
N.A.
13.3
80
73.3
66.6
N.A.
73.3
N.A.
66.6
N.A.
P-Site Similarity:
100
80
93.3
93.3
N.A.
93.3
93.3
N.A.
53.3
80
86.6
80
N.A.
80
N.A.
73.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
57
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
71.1
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
80
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
54
8
0
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
16
0
0
0
0
0
0
0
% D
% Glu:
100
0
8
8
8
85
93
0
0
24
8
0
93
0
0
% E
% Phe:
0
0
0
0
8
0
0
0
0
0
0
77
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
93
93
77
8
8
8
16
93
0
85
0
8
0
8
% K
% Leu:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
93
% L
% Met:
0
0
0
0
54
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
62
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
47
0
0
0
8
0
16
0
% S
% Thr:
0
0
0
8
0
0
0
0
0
16
0
0
0
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
16
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _