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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HSP90AA4P
All Species:
37.27
Human Site:
T253
Identified Species:
82
UniProt:
Q58FG1
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58FG1
NP_005339
418
47712
T253
G
K
T
L
V
S
V
T
K
E
D
L
E
L
P
Chimpanzee
Pan troglodytes
NP_001092042
733
84754
T546
G
K
T
L
V
S
V
T
K
E
G
L
E
L
P
Rhesus Macaque
Macaca mulatta
XP_001098219
597
68451
T410
G
K
S
L
V
S
V
T
K
E
G
L
E
L
P
Dog
Lupus familis
XP_866031
480
54525
T313
G
K
S
L
V
S
V
T
K
E
G
L
E
L
P
Cat
Felis silvestris
Mouse
Mus musculus
NP_034610
733
84769
T546
G
K
T
L
V
S
V
T
K
E
G
L
E
L
P
Rat
Rattus norvegicus
XP_002726641
259
29645
D104
N
L
C
K
I
M
K
D
I
L
E
K
K
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512830
733
84847
T546
G
K
T
L
V
S
V
T
K
E
G
L
E
L
P
Chicken
Gallus gallus
NP_001103255
728
84041
T541
G
K
T
L
V
S
V
T
K
E
G
L
E
L
P
Frog
Xenopus laevis
NP_001085598
729
84174
T542
G
K
T
L
V
S
V
T
K
E
G
L
E
L
P
Zebra Danio
Brachydanio rerio
NP_571403
726
83543
T539
G
K
N
L
V
S
V
T
K
E
G
L
E
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395168
718
82735
T533
G
K
Q
L
V
S
V
T
K
E
G
L
E
F
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
49.7
50.9
66.8
N.A.
49.5
40.6
N.A.
48.7
48.6
47.7
43.9
N.A.
N.A.
42.9
N.A.
N.A.
Protein Similarity:
100
52.1
57.9
73.7
N.A.
52.1
48.5
N.A.
51.8
51.3
50.7
50
N.A.
N.A.
49.1
N.A.
N.A.
P-Site Identity:
100
93.3
86.6
86.6
N.A.
93.3
0
N.A.
93.3
93.3
93.3
86.6
N.A.
N.A.
80
N.A.
N.A.
P-Site Similarity:
100
93.3
93.3
93.3
N.A.
93.3
26.6
N.A.
93.3
93.3
93.3
86.6
N.A.
N.A.
80
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
91
10
0
91
0
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
91
0
0
0
0
0
0
0
0
0
82
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
91
0
10
0
0
10
0
91
0
0
10
10
0
0
% K
% Leu:
0
10
0
91
0
0
0
0
0
10
0
91
0
82
0
% L
% Met:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
91
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
19
0
0
91
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
55
0
0
0
0
91
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
91
0
91
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _