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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF6 All Species: 14.24
Human Site: S369 Identified Species: 28.48
UniProt: Q58WW2 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58WW2 NP_001017977.1 860 96292 S369 S N R G R G R S R P R G G T S
Chimpanzee Pan troglodytes XP_001174803 860 96251 S369 S N R G R G R S R P R G G T S
Rhesus Macaque Macaca mulatta XP_001091583 860 96139 S369 S N R G R G R S R P R G G T S
Dog Lupus familis XP_862582 859 95606 S369 S N R G R G R S R P R G G T S
Cat Felis silvestris
Mouse Mus musculus Q9DC22 876 97569 R368 Q S N R G R G R P R P R G G T
Rat Rattus norvegicus XP_213926 871 96950 P369 S N R G R G R P R P R G G T N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513832 860 94531 P369 A S A P P T G P S S T E F E A
Chicken Gallus gallus XP_416649 828 92195 S360 E Q L P S S S S S T M S A Q A
Frog Xenopus laevis NP_001098734 763 86014 K296 K F P S S D Q K R D E V R Q P
Zebra Danio Brachydanio rerio NP_001138562 907 98726 R365 S R A R P Q T R P R G T A A Q
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121379 813 91439 L346 I A Q A R P V L Q T S L M Q R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795377 800 89350 D333 T S S Q V H Q D A S H E E L E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 93.7 N.A. 86.1 88 N.A. 78.2 68.9 64.7 62.5 N.A. N.A. 36.5 N.A. 26
Protein Similarity: 100 99.6 98.9 95.2 N.A. 89.2 91.1 N.A. 83.7 76.7 74.4 71.6 N.A. N.A. 52.7 N.A. 41.4
P-Site Identity: 100 100 100 100 N.A. 6.6 86.6 N.A. 0 6.6 6.6 6.6 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 20 93.3 N.A. 20 13.3 13.3 6.6 N.A. N.A. 20 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 9 17 9 0 0 0 0 9 0 0 0 17 9 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 9 0 9 0 9 0 0 0 0 0 % D
% Glu: 9 0 0 0 0 0 0 0 0 0 9 17 9 9 9 % E
% Phe: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 0 % F
% Gly: 0 0 0 42 9 42 17 0 0 0 9 42 50 9 0 % G
% His: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 9 0 0 0 0 9 0 0 0 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 0 % M
% Asn: 0 42 9 0 0 0 0 0 0 0 0 0 0 0 9 % N
% Pro: 0 0 9 17 17 9 0 17 17 42 9 0 0 0 9 % P
% Gln: 9 9 9 9 0 9 17 0 9 0 0 0 0 25 9 % Q
% Arg: 0 9 42 17 50 9 42 17 50 17 42 9 9 0 9 % R
% Ser: 50 25 9 9 17 9 9 42 17 17 9 9 0 0 34 % S
% Thr: 9 0 0 0 0 9 9 0 0 17 9 9 0 42 9 % T
% Val: 0 0 0 0 9 0 9 0 0 0 0 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _