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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DCAF6 All Species: 18.79
Human Site: S389 Identified Species: 37.58
UniProt: Q58WW2 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q58WW2 NP_001017977.1 860 96292 S389 T L P T V P S S P D L E V S E
Chimpanzee Pan troglodytes XP_001174803 860 96251 S389 T L P T V P S S P D L E V S E
Rhesus Macaque Macaca mulatta XP_001091583 860 96139 S389 T L P T V P S S P D L E G S E
Dog Lupus familis XP_862582 859 95606 S389 A L P A V P S S T D L E V G E
Cat Felis silvestris
Mouse Mus musculus Q9DC22 876 97569 S388 S T L P T V P S S P N L E V C
Rat Rattus norvegicus XP_213926 871 96950 S389 A L P T V P S S P N L E V G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513832 860 94531 P389 D V D G P A E P G L Q A S P S
Chicken Gallus gallus XP_416649 828 92195 T380 S T G S P P S T S L L S S P D
Frog Xenopus laevis NP_001098734 763 86014 D316 R L R G D W S D T G P R A R P
Zebra Danio Brachydanio rerio NP_001138562 907 98726 Q385 S E T T A Q A Q V S S G V A A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001121379 813 91439 A366 S R M L N D P A T R A A L C G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_795377 800 89350 R353 S R T G D S S R K P D V V P K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98.8 93.7 N.A. 86.1 88 N.A. 78.2 68.9 64.7 62.5 N.A. N.A. 36.5 N.A. 26
Protein Similarity: 100 99.6 98.9 95.2 N.A. 89.2 91.1 N.A. 83.7 76.7 74.4 71.6 N.A. N.A. 52.7 N.A. 41.4
P-Site Identity: 100 100 93.3 73.3 N.A. 6.6 80 N.A. 0 20 13.3 13.3 N.A. N.A. 0 N.A. 13.3
P-Site Similarity: 100 100 93.3 73.3 N.A. 13.3 86.6 N.A. 6.6 46.6 13.3 33.3 N.A. N.A. 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 0 9 9 9 9 9 0 0 9 17 9 9 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 9 % C
% Asp: 9 0 9 0 17 9 0 9 0 34 9 0 0 0 9 % D
% Glu: 0 9 0 0 0 0 9 0 0 0 0 42 9 0 42 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 25 0 0 0 0 9 9 0 9 9 17 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % K
% Leu: 0 50 9 9 0 0 0 0 0 17 50 9 9 0 0 % L
% Met: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 9 9 0 0 0 0 % N
% Pro: 0 0 42 9 17 50 17 9 34 17 9 0 0 25 9 % P
% Gln: 0 0 0 0 0 9 0 9 0 0 9 0 0 0 0 % Q
% Arg: 9 17 9 0 0 0 0 9 0 9 0 9 0 9 0 % R
% Ser: 42 0 0 9 0 9 67 50 17 9 9 9 17 25 9 % S
% Thr: 25 17 17 42 9 0 0 9 25 0 0 0 0 0 0 % T
% Val: 0 9 0 0 42 9 0 0 9 0 0 9 50 9 0 % V
% Trp: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _