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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF6
All Species:
19.39
Human Site:
S433
Identified Species:
38.79
UniProt:
Q58WW2
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58WW2
NP_001017977.1
860
96292
S433
S
P
T
E
S
P
H
S
T
P
L
L
S
S
P
Chimpanzee
Pan troglodytes
XP_001174803
860
96251
S433
S
P
T
E
S
P
H
S
T
P
L
L
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001091583
860
96139
S433
S
P
T
E
S
P
H
S
T
P
L
L
S
S
P
Dog
Lupus familis
XP_862582
859
95606
S433
S
S
T
E
S
P
H
S
T
S
L
L
S
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC22
876
97569
S432
A
A
I
E
S
P
R
S
S
S
L
L
S
C
P
Rat
Rattus norvegicus
XP_213926
871
96950
T433
A
I
E
S
P
R
S
T
S
L
L
S
S
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513832
860
94531
S433
E
R
Q
S
P
E
A
S
G
Q
R
P
T
H
Q
Chicken
Gallus gallus
XP_416649
828
92195
Q424
G
S
M
S
L
D
E
Q
Q
D
G
N
N
Q
H
Frog
Xenopus laevis
NP_001098734
763
86014
S360
E
A
S
E
V
A
Q
S
S
R
R
R
V
R
L
Zebra Danio
Brachydanio rerio
NP_001138562
907
98726
G429
S
V
S
S
S
S
S
G
S
S
S
T
V
T
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121379
813
91439
R410
R
R
D
N
E
A
E
R
M
E
R
T
Q
I
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795377
800
89350
K397
S
A
M
D
G
A
I
K
K
K
S
G
K
E
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
93.7
N.A.
86.1
88
N.A.
78.2
68.9
64.7
62.5
N.A.
N.A.
36.5
N.A.
26
Protein Similarity:
100
99.6
98.9
95.2
N.A.
89.2
91.1
N.A.
83.7
76.7
74.4
71.6
N.A.
N.A.
52.7
N.A.
41.4
P-Site Identity:
100
100
100
86.6
N.A.
53.3
13.3
N.A.
6.6
0
13.3
13.3
N.A.
N.A.
0
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
66.6
33.3
N.A.
13.3
6.6
26.6
33.3
N.A.
N.A.
0
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
25
0
0
0
25
9
0
0
0
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
9
9
0
9
0
0
0
9
0
0
0
0
9
% D
% Glu:
17
0
9
50
9
9
17
0
0
9
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
9
0
0
9
9
0
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
34
0
0
0
0
0
0
9
9
% H
% Ile:
0
9
9
0
0
0
9
0
0
0
0
0
0
9
0
% I
% Lys:
0
0
0
0
0
0
0
9
9
9
0
0
9
0
0
% K
% Leu:
0
0
0
0
9
0
0
0
0
9
50
42
0
0
9
% L
% Met:
0
0
17
0
0
0
0
0
9
0
0
0
0
0
9
% M
% Asn:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% N
% Pro:
0
25
0
0
17
42
0
0
0
25
0
9
0
9
42
% P
% Gln:
0
0
9
0
0
0
9
9
9
9
0
0
9
9
17
% Q
% Arg:
9
17
0
0
0
9
9
9
0
9
25
9
0
9
0
% R
% Ser:
50
17
17
34
50
9
17
59
34
25
17
9
50
34
0
% S
% Thr:
0
0
34
0
0
0
0
9
34
0
0
17
9
9
0
% T
% Val:
0
9
0
0
9
0
0
0
0
0
0
0
17
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _