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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DCAF6
All Species:
8.79
Human Site:
Y550
Identified Species:
17.58
UniProt:
Q58WW2
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q58WW2
NP_001017977.1
860
96292
Y550
S
S
E
D
V
T
K
Y
Q
E
G
V
S
A
E
Chimpanzee
Pan troglodytes
XP_001174803
860
96251
Y550
S
S
E
D
V
T
K
Y
Q
E
E
V
S
A
E
Rhesus Macaque
Macaca mulatta
XP_001091583
860
96139
Y550
S
S
E
D
V
T
K
Y
Q
E
G
V
S
A
E
Dog
Lupus familis
XP_862582
859
95606
Q550
S
E
D
V
T
T
Y
Q
E
G
T
S
A
E
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DC22
876
97569
P549
L
S
E
K
G
T
L
P
E
N
L
T
Q
N
Q
Rat
Rattus norvegicus
XP_213926
871
96950
P550
P
L
G
S
V
Q
P
P
E
G
D
S
E
T
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513832
860
94531
W550
S
L
E
E
A
S
K
W
K
E
P
G
P
G
S
Chicken
Gallus gallus
XP_416649
828
92195
P541
E
A
T
V
P
D
K
P
V
T
E
H
P
G
I
Frog
Xenopus laevis
NP_001098734
763
86014
N477
D
F
T
D
E
W
S
N
T
A
S
S
S
V
A
Zebra Danio
Brachydanio rerio
NP_001138562
907
98726
R546
S
T
P
S
G
S
G
R
S
G
T
A
E
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_001121379
813
91439
E527
S
S
M
E
N
K
Q
E
G
H
M
M
E
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_795377
800
89350
E514
F
A
F
G
D
R
M
E
D
K
K
P
M
P
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.8
93.7
N.A.
86.1
88
N.A.
78.2
68.9
64.7
62.5
N.A.
N.A.
36.5
N.A.
26
Protein Similarity:
100
99.6
98.9
95.2
N.A.
89.2
91.1
N.A.
83.7
76.7
74.4
71.6
N.A.
N.A.
52.7
N.A.
41.4
P-Site Identity:
100
93.3
100
13.3
N.A.
20
6.6
N.A.
26.6
6.6
13.3
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
93.3
100
33.3
N.A.
33.3
13.3
N.A.
53.3
13.3
13.3
20
N.A.
N.A.
33.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
9
0
0
0
0
9
0
9
9
25
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
9
34
9
9
0
0
9
0
9
0
0
0
0
% D
% Glu:
9
9
42
17
9
0
0
17
25
34
17
0
25
9
25
% E
% Phe:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
9
17
0
9
0
9
25
17
9
0
17
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
9
42
0
9
9
9
0
0
0
0
% K
% Leu:
9
17
0
0
0
0
9
0
0
0
9
0
0
0
9
% L
% Met:
0
0
9
0
0
0
9
0
0
0
9
9
9
0
0
% M
% Asn:
0
0
0
0
9
0
0
9
0
9
0
0
0
17
9
% N
% Pro:
9
0
9
0
9
0
9
25
0
0
9
9
17
17
0
% P
% Gln:
0
0
0
0
0
9
9
9
25
0
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
17
% R
% Ser:
59
42
0
17
0
17
9
0
9
0
9
25
34
0
9
% S
% Thr:
0
9
17
0
9
42
0
0
9
9
17
9
0
9
0
% T
% Val:
0
0
0
17
34
0
0
0
9
0
0
25
0
9
9
% V
% Trp:
0
0
0
0
0
9
0
9
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _