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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNDC3A
All Species:
10.91
Human Site:
S374
Identified Species:
26.67
UniProt:
Q59EK9
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59EK9
NP_001138297.1
446
49747
S374
F
M
S
T
E
P
L
S
A
E
A
S
L
S
S
Chimpanzee
Pan troglodytes
XP_001140468
454
50428
S382
F
M
S
T
E
P
L
S
A
E
A
S
L
S
S
Rhesus Macaque
Macaca mulatta
XP_001100710
483
54413
A411
L
G
G
D
L
R
A
A
L
S
L
P
T
P
L
Dog
Lupus familis
XP_537621
371
41195
A300
M
S
T
E
P
L
S
A
E
A
S
L
S
S
D
Cat
Felis silvestris
Mouse
Mus musculus
O08576
446
50000
S374
F
M
S
T
E
P
L
S
A
E
A
S
L
S
S
Rat
Rattus norvegicus
Q3B7K9
403
44774
Q332
S
A
E
V
S
L
S
Q
A
S
L
D
P
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508997
456
50767
L383
Q
L
G
G
E
A
N
L
S
Q
S
S
L
D
P
Chicken
Gallus gallus
NP_001026143
313
35560
W242
V
I
V
D
E
N
I
W
Y
N
K
C
K
R
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A7YDW0
428
48457
P356
H
R
G
S
F
P
S
P
E
P
H
I
S
L
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785586
443
49510
S351
S
I
S
P
V
S
S
S
S
G
I
S
T
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
74
68.3
81.8
N.A.
96.4
51.7
N.A.
50.4
43.9
N.A.
70.1
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
79.3
72.4
82.7
N.A.
97.5
67.2
N.A.
64.9
55.3
N.A.
81.3
N.A.
N.A.
N.A.
N.A.
50.2
P-Site Identity:
100
100
0
6.6
N.A.
100
6.6
N.A.
20
6.6
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
6.6
26.6
N.A.
100
6.6
N.A.
46.6
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
10
10
20
40
10
30
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% C
% Asp:
0
0
0
20
0
0
0
0
0
0
0
10
0
10
10
% D
% Glu:
0
0
10
10
50
0
0
0
20
30
0
0
0
0
10
% E
% Phe:
30
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
30
10
0
0
0
0
0
10
0
0
0
10
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
10
% H
% Ile:
0
20
0
0
0
0
10
0
0
0
10
10
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
10
0
10
0
0
% K
% Leu:
10
10
0
0
10
20
30
10
10
0
20
10
40
10
10
% L
% Met:
10
30
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
10
0
0
0
0
0
% N
% Pro:
0
0
0
10
10
40
0
10
0
10
0
10
10
10
10
% P
% Gln:
10
0
0
0
0
0
0
10
0
10
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
0
0
0
0
0
0
10
0
% R
% Ser:
20
10
40
10
10
10
40
40
20
20
20
50
20
40
30
% S
% Thr:
0
0
10
30
0
0
0
0
0
0
0
0
20
0
10
% T
% Val:
10
0
10
10
10
0
0
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _