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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TNNI3K
All Species:
13.64
Human Site:
S394
Identified Species:
30
UniProt:
Q59H18
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q59H18
NP_001106279.1
936
104179
S394
A
K
E
I
I
Q
I
S
G
T
E
S
L
T
K
Chimpanzee
Pan troglodytes
XP_513493
949
105567
S407
A
K
E
I
I
Q
I
S
G
T
E
S
L
T
K
Rhesus Macaque
Macaca mulatta
XP_001097254
949
105560
S407
A
K
E
I
I
Q
I
S
G
T
E
S
L
T
K
Dog
Lupus familis
XP_537112
1087
119299
S562
A
K
E
I
I
Q
I
S
G
I
E
S
M
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q5GIG6
834
92569
Q327
L
V
K
F
L
L
D
Q
N
A
V
N
I
N
H
Rat
Rattus norvegicus
Q7TQP6
835
92713
Q328
L
V
K
F
L
L
D
Q
N
A
V
N
I
N
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001339957
835
92821
Q328
M
V
K
Y
L
L
G
Q
N
A
M
S
I
N
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_001021182
850
93167
K343
E
L
V
S
F
L
M
K
Y
P
G
V
D
P
N
Sea Urchin
Strong. purpuratus
XP_782227
862
95496
Y355
K
N
I
E
L
V
K
Y
L
L
S
Q
E
G
V
Poplar Tree
Populus trichocarpa
XP_002336079
539
60951
R32
V
F
N
D
V
F
Y
R
L
K
E
S
N
D
E
Maize
Zea mays
NP_001152032
543
61643
H36
R
A
S
N
P
D
C
H
E
V
Q
R
K
I
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.2
96.5
80.1
N.A.
80.7
81.3
N.A.
N.A.
N.A.
N.A.
75.7
N.A.
N.A.
N.A.
36.7
51.1
Protein Similarity:
100
98.3
97.2
82.6
N.A.
84.4
85.3
N.A.
N.A.
N.A.
N.A.
83.7
N.A.
N.A.
N.A.
55
65.6
P-Site Identity:
100
100
100
86.6
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
0
0
P-Site Similarity:
100
100
100
93.3
N.A.
26.6
26.6
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
6.6
6.6
Percent
Protein Identity:
23.6
22.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
37.2
36.2
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
37
10
0
0
0
0
0
0
0
28
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% C
% Asp:
0
0
0
10
0
10
19
0
0
0
0
0
10
10
0
% D
% Glu:
10
0
37
10
0
0
0
0
10
0
46
0
10
0
10
% E
% Phe:
0
10
0
19
10
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
10
0
37
0
10
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
28
% H
% Ile:
0
0
10
37
37
0
37
0
0
10
0
0
28
10
0
% I
% Lys:
10
37
28
0
0
0
10
10
0
10
0
0
10
0
37
% K
% Leu:
19
10
0
0
37
37
0
0
19
10
0
0
28
0
0
% L
% Met:
10
0
0
0
0
0
10
0
0
0
10
0
10
0
0
% M
% Asn:
0
10
10
10
0
0
0
0
28
0
0
19
10
28
10
% N
% Pro:
0
0
0
0
10
0
0
0
0
10
0
0
0
10
0
% P
% Gln:
0
0
0
0
0
37
0
28
0
0
10
10
0
0
0
% Q
% Arg:
10
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% R
% Ser:
0
0
10
10
0
0
0
37
0
0
10
55
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
28
0
0
0
37
0
% T
% Val:
10
28
10
0
10
10
0
0
0
10
19
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
10
10
10
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _