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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM41B All Species: 10.3
Human Site: S10 Identified Species: 18.89
UniProt: Q5BJD5 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5BJD5 NP_055827.1 291 32513 S10 K G R V A E R S Q L G A H H T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851421 291 32339 S10 K G R V A E R S Q T G A L H T
Cat Felis silvestris
Mouse Mus musculus Q8K1A5 291 32411 S10 K G R V A D R S P T E M L H S
Rat Rattus norvegicus Q5FVN2 291 32493 S10 K G R V A E R S Q T E M L H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518100 250 28222
Chicken Gallus gallus Q5ZIL6 269 30250
Frog Xenopus laevis Q5U4K5 278 31193 G10 V H E R S H T G G H T F Q C N
Zebra Danio Brachydanio rerio A1A5V7 282 31476 N8 M A K K R A G N R E T E S S P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VX39 320 35815 L38 D Q V A T P L L P Q V P P Q E
Honey Bee Apis mellifera XP_392926 259 29291
Nematode Worm Caenorhab. elegans O62126 246 27484
Sea Urchin Strong. purpuratus XP_795018 297 33554 P16 R R K S R E G P K V D Q R V D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8L586 287 32120 R14 L T G D G G A R Q L V K D E E
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 93.8 N.A. 90.3 93.1 N.A. 80.7 82.4 82.1 72.5 N.A. 44.3 48.4 45 56.2
Protein Similarity: 100 N.A. N.A. 95.5 N.A. 93.8 95.1 N.A. 83.8 87.2 86.9 83.1 N.A. 62.1 70.4 61.5 72.7
P-Site Identity: 100 N.A. N.A. 86.6 N.A. 53.3 66.6 N.A. 0 0 0 0 N.A. 0 0 0 6.6
P-Site Similarity: 100 N.A. N.A. 86.6 N.A. 66.6 73.3 N.A. 0 0 6.6 20 N.A. 0 0 0 33.3
Percent
Protein Identity: N.A. N.A. N.A. 31.6 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 54.3 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 8 31 8 8 0 0 0 0 16 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 8 0 0 8 0 8 0 0 0 0 8 0 8 0 8 % D
% Glu: 0 0 8 0 0 31 0 0 0 8 16 8 0 8 16 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 31 8 0 8 8 16 8 8 0 16 0 0 0 0 % G
% His: 0 8 0 0 0 8 0 0 0 8 0 0 8 31 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 31 0 16 8 0 0 0 0 8 0 0 8 0 0 0 % K
% Leu: 8 0 0 0 0 0 8 8 0 16 0 0 24 0 0 % L
% Met: 8 0 0 0 0 0 0 0 0 0 0 16 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % N
% Pro: 0 0 0 0 0 8 0 8 16 0 0 8 8 0 8 % P
% Gln: 0 8 0 0 0 0 0 0 31 8 0 8 8 8 0 % Q
% Arg: 8 8 31 8 16 0 31 8 8 0 0 0 8 0 0 % R
% Ser: 0 0 0 8 8 0 0 31 0 0 0 0 8 8 16 % S
% Thr: 0 8 0 0 8 0 8 0 0 24 16 0 0 0 16 % T
% Val: 8 0 8 31 0 0 0 0 0 8 16 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _