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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41B
All Species:
20.61
Human Site:
Y178
Identified Species:
37.78
UniProt:
Q5BJD5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BJD5
NP_055827.1
291
32513
Y178
G
R
P
V
V
Y
K
Y
L
T
E
K
A
V
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851421
291
32339
Y178
G
R
P
V
V
Y
K
Y
L
T
E
K
A
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1A5
291
32411
Y178
G
R
P
V
V
Y
K
Y
L
T
E
K
A
V
K
Rat
Rattus norvegicus
Q5FVN2
291
32493
Y178
G
R
P
V
V
Y
K
Y
L
T
E
K
A
V
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518100
250
28222
W145
L
T
E
K
A
V
R
W
S
Q
Q
V
E
R
H
Chicken
Gallus gallus
Q5ZIL6
269
30250
W164
L
T
E
K
A
V
K
W
S
E
Q
V
E
R
H
Frog
Xenopus laevis
Q5U4K5
278
31193
K169
V
Y
K
Y
L
S
D
K
A
I
K
W
S
Q
Q
Zebra Danio
Brachydanio rerio
A1A5V7
282
31476
Y169
G
R
P
M
V
Y
K
Y
L
T
E
R
A
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
F206
G
R
R
L
I
R
H
F
W
P
K
K
T
S
E
Honey Bee
Apis mellifera
XP_392926
259
29291
E154
Y
F
P
E
K
A
R
E
W
T
L
T
V
K
K
Nematode Worm
Caenorhab. elegans
O62126
246
27484
I140
L
Q
K
F
P
E
R
I
A
K
W
Q
D
D
L
Sea Urchin
Strong. purpuratus
XP_795018
297
33554
Y184
G
V
Q
L
V
Q
K
Y
I
P
E
R
V
E
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
L176
G
R
P
L
V
N
W
L
W
P
E
K
L
R
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.8
N.A.
90.3
93.1
N.A.
80.7
82.4
82.1
72.5
N.A.
44.3
48.4
45
56.2
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
93.8
95.1
N.A.
83.8
87.2
86.9
83.1
N.A.
62.1
70.4
61.5
72.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
0
6.6
0
80
N.A.
20
20
0
40
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
20
20
26.6
93.3
N.A.
53.3
26.6
20
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
16
8
0
0
16
0
0
0
39
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
8
8
0
% D
% Glu:
0
0
16
8
0
8
0
8
0
8
54
0
16
8
8
% E
% Phe:
0
8
0
8
0
0
0
8
0
0
0
0
0
0
8
% F
% Gly:
62
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
16
% H
% Ile:
0
0
0
0
8
0
0
8
8
8
0
0
0
0
0
% I
% Lys:
0
0
16
16
8
0
54
8
0
8
16
47
0
8
54
% K
% Leu:
24
0
0
24
8
0
0
8
39
0
8
0
8
0
8
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
54
0
8
0
0
0
0
24
0
0
0
0
0
% P
% Gln:
0
8
8
0
0
8
0
0
0
8
16
8
0
16
8
% Q
% Arg:
0
54
8
0
0
8
24
0
0
0
0
16
0
24
0
% R
% Ser:
0
0
0
0
0
8
0
0
16
0
0
0
8
8
0
% S
% Thr:
0
16
0
0
0
0
0
0
0
47
0
8
8
0
0
% T
% Val:
8
8
0
31
54
16
0
0
0
0
0
16
16
31
0
% V
% Trp:
0
0
0
0
0
0
8
16
24
0
8
8
0
0
0
% W
% Tyr:
8
8
0
8
0
39
0
47
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _