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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM41B
All Species:
18.48
Human Site:
Y252
Identified Species:
33.89
UniProt:
Q5BJD5
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BJD5
NP_055827.1
291
32513
Y252
I
K
A
G
T
T
L
Y
Q
L
T
T
A
G
E
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851421
291
32339
Y252
I
K
A
G
T
T
L
Y
Q
L
T
T
A
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1A5
291
32411
H252
I
K
A
G
T
T
L
H
Q
L
T
T
A
G
E
Rat
Rattus norvegicus
Q5FVN2
291
32493
Y252
I
K
A
G
T
T
L
Y
Q
L
T
T
A
G
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518100
250
28222
A219
Q
L
T
T
A
G
E
A
V
S
W
N
S
V
F
Chicken
Gallus gallus
Q5ZIL6
269
30250
A238
Q
L
T
T
A
G
E
A
V
S
W
N
S
L
F
Frog
Xenopus laevis
Q5U4K5
278
31193
T243
T
T
L
Y
Q
L
T
T
A
G
E
A
V
S
W
Zebra Danio
Brachydanio rerio
A1A5V7
282
31476
Y243
I
N
A
G
T
T
L
Y
K
L
T
T
A
G
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VX39
320
35815
Q280
I
Q
A
G
K
T
L
Q
K
M
T
S
S
S
E
Honey Bee
Apis mellifera
XP_392926
259
29291
G228
Q
N
L
T
L
S
T
G
W
S
W
K
S
V
I
Nematode Worm
Caenorhab. elegans
O62126
246
27484
T214
T
L
E
Q
L
S
H
T
S
V
A
W
S
W
S
Sea Urchin
Strong. purpuratus
XP_795018
297
33554
Y258
I
Q
A
G
T
T
L
Y
Q
L
T
H
A
G
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8L586
287
32120
G250
V
R
A
G
L
A
L
G
D
L
R
S
V
K
D
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
93.8
N.A.
90.3
93.1
N.A.
80.7
82.4
82.1
72.5
N.A.
44.3
48.4
45
56.2
Protein Similarity:
100
N.A.
N.A.
95.5
N.A.
93.8
95.1
N.A.
83.8
87.2
86.9
83.1
N.A.
62.1
70.4
61.5
72.7
P-Site Identity:
100
N.A.
N.A.
100
N.A.
93.3
100
N.A.
0
0
0
86.6
N.A.
46.6
0
0
80
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
6.6
6.6
0
93.3
N.A.
80
13.3
20
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.6
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.3
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
53.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
62
0
16
8
0
16
8
0
8
8
47
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
16
% D
% Glu:
0
0
8
0
0
0
16
0
0
0
8
0
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
0
62
0
16
0
16
0
8
0
0
0
47
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
8
0
0
0
% H
% Ile:
54
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
31
0
0
8
0
0
0
16
0
0
8
0
8
0
% K
% Leu:
0
24
16
0
24
8
62
0
0
54
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
16
0
0
0
0
0
0
0
0
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
24
16
0
8
8
0
0
8
39
0
0
0
0
0
0
% Q
% Arg:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
0
0
16
0
0
8
24
0
16
39
16
8
% S
% Thr:
16
8
16
24
47
54
16
16
0
0
54
39
0
0
0
% T
% Val:
8
0
0
0
0
0
0
0
16
8
0
0
16
16
0
% V
% Trp:
0
0
0
0
0
0
0
0
8
0
24
8
0
8
8
% W
% Tyr:
0
0
0
8
0
0
0
39
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _