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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133B
All Species:
24.24
Human Site:
S121
Identified Species:
59.26
UniProt:
Q5BKY9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BKY9
NP_001035146.1
247
28385
S121
S
S
S
S
S
S
D
S
E
D
E
D
K
K
Q
Chimpanzee
Pan troglodytes
XP_519200
223
25539
S101
K
K
K
E
K
K
K
S
G
R
Y
S
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001100396
237
27161
S111
S
S
S
S
S
S
D
S
E
D
E
D
K
K
Q
Dog
Lupus familis
XP_852344
247
28388
S121
S
S
S
S
S
S
D
S
D
D
E
D
K
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
S121
S
S
S
S
S
S
D
S
E
D
E
D
K
K
Q
Rat
Rattus norvegicus
Q505I5
245
28015
S121
S
S
S
S
S
S
D
S
E
E
E
D
K
K
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
E108
S
S
S
M
D
S
D
E
E
D
K
K
Q
G
K
Chicken
Gallus gallus
Q5ZLM8
250
28336
S121
S
D
S
S
S
S
A
S
D
S
E
D
E
D
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
S130
S
S
D
S
S
S
S
S
S
S
D
A
E
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
D57
S
S
L
A
F
W
E
D
K
I
N
I
K
F
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
95.5
96.7
N.A.
87.4
87
N.A.
50.3
78.4
N.A.
59
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
89.8
95.9
97.9
N.A.
93.1
93.5
N.A.
62.5
86.8
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
6.6
100
93.3
N.A.
100
93.3
N.A.
46.6
53.3
N.A.
40
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
6.6
100
100
N.A.
100
100
N.A.
66.6
73.3
N.A.
53.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
10
0
0
0
0
10
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
10
0
10
0
60
10
20
50
10
60
0
20
10
% D
% Glu:
0
0
0
10
0
0
10
10
50
10
60
0
20
0
0
% E
% Phe:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% I
% Lys:
10
10
10
0
10
10
10
0
10
0
10
10
60
50
20
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
50
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
10
% R
% Ser:
90
80
70
70
70
80
10
80
10
20
0
10
10
10
10
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _