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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM133B All Species: 17.58
Human Site: S139 Identified Species: 42.96
UniProt: Q5BKY9 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5BKY9 NP_001035146.1 247 28385 S139 R K K K K N R S H K S S E S S
Chimpanzee Pan troglodytes XP_519200 223 25539 S116 S S S S D S S S S S S D S E D
Rhesus Macaque Macaca mulatta XP_001100396 237 27161 S129 R K K K K N R S H K S S E S S
Dog Lupus familis XP_852344 247 28388 S139 K K K K K N R S H K S S E S S
Cat Felis silvestris
Mouse Mus musculus Q9CVI2 245 27934 S137 K R R K K K K S R C H K S P E
Rat Rattus norvegicus Q505I5 245 28015 S137 K R R K K K K S H C H K S P E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520774 262 28329 P124 K R K K K Y R P H K S S E G S
Chicken Gallus gallus Q5ZLM8 250 28336 S142 K K K K H R S S R K S S S S S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A1A5I1 259 29813 K150 L K K K K K R K R S S T R K A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793119 179 21138 E72 E D L R K T R E K Q L G S S S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.8 95.5 96.7 N.A. 87.4 87 N.A. 50.3 78.4 N.A. 59 N.A. N.A. N.A. N.A. 36.4
Protein Similarity: 100 89.8 95.9 97.9 N.A. 93.1 93.5 N.A. 62.5 86.8 N.A. 75.6 N.A. N.A. N.A. N.A. 57.4
P-Site Identity: 100 13.3 100 93.3 N.A. 20 26.6 N.A. 66.6 60 N.A. 40 N.A. N.A. N.A. N.A. 26.6
P-Site Similarity: 100 20 100 100 N.A. 46.6 53.3 N.A. 80 66.6 N.A. 53.3 N.A. N.A. N.A. N.A. 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % C
% Asp: 0 10 0 0 10 0 0 0 0 0 0 10 0 0 10 % D
% Glu: 10 0 0 0 0 0 0 10 0 0 0 0 40 10 20 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % G
% His: 0 0 0 0 10 0 0 0 50 0 20 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 50 50 60 80 80 30 20 10 10 50 0 20 0 10 0 % K
% Leu: 10 0 10 0 0 0 0 0 0 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 10 0 0 0 0 0 20 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % Q
% Arg: 20 30 20 10 0 10 60 0 30 0 0 0 10 0 0 % R
% Ser: 10 10 10 10 0 10 20 70 10 20 70 50 50 50 60 % S
% Thr: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _