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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133B
All Species:
22.25
Human Site:
S242
Identified Species:
54.4
UniProt:
Q5BKY9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BKY9
NP_001035146.1
247
28385
S242
K
K
K
K
A
A
S
S
S
P
D
S
P
_
_
Chimpanzee
Pan troglodytes
XP_519200
223
25539
Rhesus Macaque
Macaca mulatta
XP_001100396
237
27161
S232
K
K
K
K
A
A
S
S
S
P
D
S
P
_
_
Dog
Lupus familis
XP_852344
247
28388
S242
K
K
K
K
A
A
S
S
S
P
D
S
P
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
S240
K
K
K
K
A
A
S
S
S
S
D
S
P
_
_
Rat
Rattus norvegicus
Q505I5
245
28015
S240
K
K
K
K
A
A
S
S
S
S
D
S
P
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
R227
G
V
R
G
S
Y
L
R
I
G
S
V
A
A
L
Chicken
Gallus gallus
Q5ZLM8
250
28336
S245
K
K
K
K
A
A
G
S
N
S
D
L
E
_
_
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
T253
S
K
K
K
K
R
K
T
S
S
S
E
L
D
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
95.5
96.7
N.A.
87.4
87
N.A.
50.3
78.4
N.A.
59
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
89.8
95.9
97.9
N.A.
93.1
93.5
N.A.
62.5
86.8
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
100
N.A.
92.3
92.3
N.A.
0
61.5
N.A.
28.5
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
0
100
100
N.A.
92.3
92.3
N.A.
13.3
69.2
N.A.
35.7
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
60
60
0
0
0
0
0
0
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
60
0
0
10
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
10
0
0
10
0
0
10
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
60
70
70
70
10
0
10
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
10
0
0
0
0
10
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
30
0
0
50
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
10
0
50
60
60
40
20
50
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
60
70
% _