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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM133B
All Species:
6.67
Human Site:
T168
Identified Species:
16.3
UniProt:
Q5BKY9
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5BKY9
NP_001035146.1
247
28385
T168
K
K
K
S
K
D
G
T
E
K
E
K
D
I
K
Chimpanzee
Pan troglodytes
XP_519200
223
25539
S145
R
S
H
K
S
S
E
S
S
M
S
E
T
E
S
Rhesus Macaque
Macaca mulatta
XP_001100396
237
27161
T158
K
K
K
S
K
D
G
T
E
K
E
K
D
I
K
Dog
Lupus familis
XP_852344
247
28388
N168
K
K
K
S
K
D
A
N
E
K
E
K
D
I
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CVI2
245
27934
D166
K
K
K
K
K
S
K
D
V
T
E
R
E
K
D
Rat
Rattus norvegicus
Q505I5
245
28015
D166
K
K
K
K
K
S
K
D
I
T
E
R
E
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001520774
262
28329
L153
L
L
Q
L
G
L
L
L
S
C
P
R
T
G
G
Chicken
Gallus gallus
Q5ZLM8
250
28336
E171
K
K
S
K
E
E
H
E
K
E
K
D
G
K
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1A5I1
259
29813
K179
S
F
K
K
K
R
K
K
T
D
G
E
K
D
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793119
179
21138
S101
K
R
E
R
S
P
S
S
S
S
S
S
Y
Q
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.8
95.5
96.7
N.A.
87.4
87
N.A.
50.3
78.4
N.A.
59
N.A.
N.A.
N.A.
N.A.
36.4
Protein Similarity:
100
89.8
95.9
97.9
N.A.
93.1
93.5
N.A.
62.5
86.8
N.A.
75.6
N.A.
N.A.
N.A.
N.A.
57.4
P-Site Identity:
100
0
100
86.6
N.A.
33.3
33.3
N.A.
0
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
20
100
86.6
N.A.
46.6
46.6
N.A.
13.3
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
30
0
20
0
10
0
10
30
10
20
% D
% Glu:
0
0
10
0
10
10
10
10
30
10
50
20
20
10
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
20
0
0
0
10
0
10
10
10
% G
% His:
0
0
10
0
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
0
0
0
0
30
0
% I
% Lys:
70
60
60
50
60
0
30
10
10
30
10
30
10
30
40
% K
% Leu:
10
10
0
10
0
10
10
10
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% N
% Pro:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% Q
% Arg:
10
10
0
10
0
10
0
0
0
0
0
30
0
0
0
% R
% Ser:
10
10
10
30
20
30
10
20
30
10
20
10
0
0
20
% S
% Thr:
0
0
0
0
0
0
0
20
10
20
0
0
20
0
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _