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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FLG2
All Species:
5.76
Human Site:
S499
Identified Species:
31.67
UniProt:
Q5D862
Number Species:
4
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5D862
NP_001014364.1
2391
248073
S499
F
G
Q
C
G
S
G
S
G
Q
S
S
G
F
G
Chimpanzee
Pan troglodytes
XP_524874
2857
282705
S498
H
G
Q
H
G
S
R
S
G
Q
S
S
R
G
E
Rhesus Macaque
Macaca mulatta
XP_001109011
2265
236397
C453
V
A
G
S
S
Q
T
C
S
Q
Y
G
S
R
S
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q2VIS4
2362
251353
S501
S
G
R
H
G
S
G
S
G
Q
S
S
S
S
R
Rat
Rattus norvegicus
XP_238235
804
88265
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
40.2
79.4
N.A.
N.A.
40.6
20.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
51.1
82.9
N.A.
N.A.
52.7
26.4
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
60
6.6
N.A.
N.A.
60
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
60
6.6
N.A.
N.A.
66.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
20
0
0
0
20
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% E
% Phe:
20
0
0
0
0
0
0
0
0
0
0
0
0
20
0
% F
% Gly:
0
60
20
0
60
0
40
0
60
0
0
20
20
20
20
% G
% His:
20
0
0
40
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
40
0
0
20
0
0
0
80
0
0
0
0
0
% Q
% Arg:
0
0
20
0
0
0
20
0
0
0
0
0
20
20
20
% R
% Ser:
20
0
0
20
20
60
0
60
20
0
60
60
40
20
20
% S
% Thr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% T
% Val:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _