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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IGSF11
All Species:
22.73
Human Site:
S270
Identified Species:
62.5
UniProt:
Q5DX21
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5DX21
NP_001015887.1
431
46124
S270
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Chimpanzee
Pan troglodytes
XP_526273
431
46163
S270
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001103243
600
63783
S439
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Dog
Lupus familis
XP_850115
555
59464
S393
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P0C673
428
46049
S270
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Rat
Rattus norvegicus
Q5U2P2
428
46003
S270
G
A
F
F
Y
W
R
S
K
N
K
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9PWR4
335
36491
V184
D
E
N
T
L
T
P
V
T
E
Y
F
N
P
D
Frog
Xenopus laevis
Q91664
318
34411
I167
E
E
G
M
P
R
P
I
Y
S
W
N
R
V
E
Zebra Danio
Brachydanio rerio
Q90Y50
372
40645
R221
Y
R
C
Q
A
K
N
R
V
G
T
E
E
C
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
70
73.6
N.A.
88.6
89
N.A.
N.A.
28
29
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
71.1
75.3
N.A.
93
93.2
N.A.
N.A.
42
42.6
51
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
6.6
13.3
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
0
12
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
12
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
12
23
0
0
0
0
0
0
0
12
0
78
78
67
78
% E
% Phe:
0
0
67
67
0
0
0
0
0
0
0
12
0
0
0
% F
% Gly:
67
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
12
0
0
67
0
67
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
12
0
0
0
12
0
0
67
0
12
12
0
0
% N
% Pro:
0
0
0
0
12
0
23
0
0
0
0
0
0
12
0
% P
% Gln:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
12
0
0
0
12
67
12
0
0
0
0
12
0
0
% R
% Ser:
0
0
0
0
0
0
0
67
0
12
0
0
0
0
0
% S
% Thr:
0
0
0
12
0
12
0
0
12
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
12
12
0
0
0
0
12
12
% V
% Trp:
0
0
0
0
0
67
0
0
0
0
12
0
0
0
0
% W
% Tyr:
12
0
0
0
67
0
0
0
12
0
12
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _