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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEST
All Species:
34.55
Human Site:
Y254
Identified Species:
84.44
UniProt:
Q5EB52
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5EB52
NP_002393.2
335
38830
Y254
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Chimpanzee
Pan troglodytes
XP_519382
422
47494
Y341
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Rhesus Macaque
Macaca mulatta
XP_001098320
326
37560
Y245
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Dog
Lupus familis
XP_848679
335
38814
Y254
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Cat
Felis silvestris
Mouse
Mus musculus
NP_032616
335
38889
Y254
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Rat
Rattus norvegicus
NP_001009617
335
38861
Y254
V
I
D
S
L
L
Q
Y
I
N
Q
R
K
K
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511333
326
37143
Y245
V
A
G
S
L
L
Q
Y
I
N
Q
R
K
Q
Q
Chicken
Gallus gallus
XP_425258
302
34599
Y221
V
V
D
S
I
L
Q
Y
I
N
Q
R
K
K
H
Frog
Xenopus laevis
NP_001092163
326
37893
F245
V
I
D
S
V
L
Q
F
I
N
Q
R
R
K
Y
Zebra Danio
Brachydanio rerio
NP_571118
344
39251
Y263
V
M
D
S
L
L
Q
Y
I
N
Q
R
L
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77
97
99
N.A.
97.9
98.5
N.A.
75.8
68.9
68.9
71.2
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
77
97
100
N.A.
99.4
99.6
N.A.
84.4
79.6
83.5
83.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
73.3
80
73.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
80
93.3
100
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
90
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
60
% F
% Gly:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
20
% H
% Ile:
0
70
0
0
10
0
0
0
100
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
80
90
0
% K
% Leu:
0
0
0
0
80
100
0
0
0
0
0
0
10
0
0
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
100
0
0
0
100
0
0
10
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
100
10
0
0
% R
% Ser:
0
0
0
100
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
100
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _