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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CENPW All Species: 22.12
Human Site: T60 Identified Species: 69.52
UniProt: Q5EE01 Number Species: 7
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5EE01 NP_001012525.1 88 10061 T60 R L A E E S R T N A C A S K C
Chimpanzee Pan troglodytes XP_001166171 103 11817 T75 R L A E E S R T N A C A S K C
Rhesus Macaque Macaca mulatta XP_001107096 88 10073 T60 R L A E E S R T N A C E S K C
Dog Lupus familis XP_868776 95 11103 Y73 K L T F R S D Y K A R F S E L
Cat Felis silvestris
Mouse Mus musculus Q3URR0 86 9715 T58 R L A E E S R T N A C E S K S
Rat Rattus norvegicus A1L1L1 86 9784 T58 K L A E E S R T N A C E S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_429872 76 8725 T48 R L A E E A R T N A F E N K S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002665002 75 8464 V47 R L A E E C R V K A F E E K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 85.4 96.5 34.7 N.A. 71.5 71.5 N.A. N.A. 54.5 N.A. 42 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 85.4 98.8 51.5 N.A. 80.6 79.5 N.A. N.A. 68.1 N.A. 51.1 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 26.6 N.A. 86.6 80 N.A. N.A. 66.6 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 93.3 40 N.A. 86.6 86.6 N.A. N.A. 80 N.A. 53.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 88 0 0 13 0 0 0 100 0 25 0 0 0 % A
% Cys: 0 0 0 0 0 13 0 0 0 0 63 0 0 0 38 % C
% Asp: 0 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 88 88 0 0 0 0 0 0 63 13 13 0 % E
% Phe: 0 0 0 13 0 0 0 0 0 0 25 13 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 25 0 0 0 0 0 0 0 25 0 0 0 0 88 0 % K
% Leu: 0 100 0 0 0 0 0 0 0 0 0 0 0 0 13 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 75 0 0 0 13 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 75 0 0 0 13 0 88 0 0 0 13 0 0 0 0 % R
% Ser: 0 0 0 0 0 75 0 0 0 0 0 0 75 0 50 % S
% Thr: 0 0 13 0 0 0 0 75 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 13 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _