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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESCO1
All Species:
9.09
Human Site:
S200
Identified Species:
25
UniProt:
Q5FWF5
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5FWF5
NP_443143.2
840
94983
S200
V
I
N
E
V
I
N
S
P
K
G
K
K
R
K
Chimpanzee
Pan troglodytes
XP_523883
839
94987
S199
V
I
N
E
V
I
N
S
P
K
G
K
K
R
K
Rhesus Macaque
Macaca mulatta
XP_001091733
840
94911
S200
V
I
N
E
V
I
D
S
P
K
G
K
K
R
K
Dog
Lupus familis
XP_547645
900
101219
P258
T
N
E
V
I
N
S
P
K
G
K
K
R
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q69Z69
843
94980
P203
T
N
E
V
I
N
S
P
K
G
K
K
R
K
V
Rat
Rattus norvegicus
NP_001119771
319
36659
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507407
288
32617
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5SPR8
609
68341
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791750
838
93461
Q209
K
V
Q
L
S
S
G
Q
M
S
G
V
K
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.3
81.3
N.A.
75.9
35.5
N.A.
30.9
N.A.
N.A.
31.5
N.A.
N.A.
N.A.
N.A.
25.1
Protein Similarity:
100
99.4
98.2
86
N.A.
85.4
37.3
N.A.
32.9
N.A.
N.A.
47.7
N.A.
N.A.
N.A.
N.A.
43.8
P-Site Identity:
100
100
93.3
6.6
N.A.
6.6
0
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
33.3
0
N.A.
0
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
23
34
0
0
0
0
0
0
0
0
0
0
12
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
12
0
0
23
45
0
0
12
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
34
0
0
23
34
0
0
0
0
0
0
0
0
0
% I
% Lys:
12
0
0
0
0
0
0
0
23
34
23
56
45
23
34
% K
% Leu:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% M
% Asn:
0
23
34
0
0
23
23
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
23
34
0
0
0
0
0
0
% P
% Gln:
0
0
12
0
0
0
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
23
34
0
% R
% Ser:
0
0
0
0
12
12
23
34
0
12
0
0
0
0
0
% S
% Thr:
23
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
34
12
0
23
34
0
0
0
0
0
0
12
0
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _