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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ARSH All Species: 27.58
Human Site: T316 Identified Species: 60.67
UniProt: Q5FYA8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5FYA8 NP_001011719.1 562 63525 T316 Q E R L A N H T L V Y F T S D
Chimpanzee Pan troglodytes XP_520911 562 63294 T316 Q E R L A N H T L V Y F T S D
Rhesus Macaque Macaca mulatta XP_001116139 540 61653 L305 V G K I L D A L D R E C L A N
Dog Lupus familis XP_548838 639 70828 T394 E N G L K N T T F T Y F T S D
Cat Felis silvestris
Mouse Mus musculus P50427 624 66572 T343 E L G L A R E T L V Y F T S D
Rat Rattus norvegicus P15589 577 62660 T334 K L G L A N N T L V Y L T S D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514452 597 66548 T329 K E S L R F N T L V Y F T S D
Chicken Gallus gallus NP_989703 590 66706 T343 K K G L K K N T L V Y F A S D
Frog Xenopus laevis NP_001086084 586 65282 T337 G A G L T N N T L I Y F A S D
Zebra Danio Brachydanio rerio Q08CJ7 523 59480 K300 R D T G S L N K T V V L F T S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus P50473 567 62459 T316 D N D I D D N T V I F F T S D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.2 82.9 55.7 N.A. 45.9 48.1 N.A. 70 61.6 55.6 20.1 N.A. N.A. N.A. N.A. 27.6
Protein Similarity: 100 98.4 86.6 69.8 N.A. 57.6 62.7 N.A. 79.4 75.5 70.4 37 N.A. N.A. N.A. N.A. 42.3
P-Site Identity: 100 100 0 53.3 N.A. 66.6 66.6 N.A. 66.6 53.3 53.3 6.6 N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: 100 100 33.3 60 N.A. 73.3 80 N.A. 80 73.3 66.6 40 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 0 0 37 0 10 0 0 0 0 0 19 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % C
% Asp: 10 10 10 0 10 19 0 0 10 0 0 0 0 0 82 % D
% Glu: 19 28 0 0 0 0 10 0 0 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 10 0 0 10 0 10 73 10 0 0 % F
% Gly: 10 10 46 10 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 19 0 0 0 0 0 19 0 0 0 0 0 % I
% Lys: 28 10 10 0 19 10 0 10 0 0 0 0 0 0 0 % K
% Leu: 0 19 0 73 10 10 0 10 64 0 0 19 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 19 0 0 0 46 55 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 19 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 19 0 10 10 0 0 0 10 0 0 0 0 0 % R
% Ser: 0 0 10 0 10 0 0 0 0 0 0 0 0 82 10 % S
% Thr: 0 0 10 0 10 0 10 82 10 10 0 0 64 10 0 % T
% Val: 10 0 0 0 0 0 0 0 10 64 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 73 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _