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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RNASE13 All Species: 4.55
Human Site: Y135 Identified Species: 25
UniProt: Q5GAN3 Number Species: 4
    Phosphosite Substitution
    Charge Score: -0.75
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5GAN3 NP_001012264.1 156 17845 Y135 T L T N Q K L Y L L C S R K Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001094063 156 17945 Y135 T L T N Q K L Y L L C S R K Y
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q5GAM7 153 17574 R133 N S T L T N Q R L Y L L C S R
Rat Rattus norvegicus Q5GAL7 153 17427 R133 N S T L T N Q R L Y L L C S R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515593 162 17989 R142 T V H V Q S H R V W L L C S S
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 84.6 N.A. N.A. 69.8 68.5 N.A. 39.5 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 N.A. 94.2 N.A. N.A. 81.4 82 N.A. 61.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 N.A. 100 N.A. N.A. 13.3 13.3 N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 N.A. 100 N.A. N.A. 13.3 13.3 N.A. 26.6 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 40 0 60 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 20 0 0 0 20 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 40 0 0 0 0 0 0 0 40 0 % K
% Leu: 0 40 0 40 0 0 40 0 80 40 60 60 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 40 0 0 40 0 40 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 60 0 40 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 60 0 0 0 0 40 0 40 % R
% Ser: 0 40 0 0 0 20 0 0 0 0 0 40 0 60 20 % S
% Thr: 60 0 80 0 40 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 20 0 20 0 0 0 0 20 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 20 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 40 0 40 0 0 0 0 40 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _